Spirocyclization, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, α,β-unsaturated ketones, Spirocyclohexanonepyrazolones, 2-fluorobenzoic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition, Spirocyclization Trifluoromethylthiolation, substituted 2,4-dihydro-3H-pyrazol-3-one, 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide, (R)-4-(3,5-dimethoxybenzyl)-2,5-diphenyl-4-((trifluoromethyl)thio)-2,4-dihydro-3H-pyrazol-3-one, (9S)-9-hydroxy-6′-methoxy-1-[2-oxo-2-[(triphenylmethyl)amino]ethyl]-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation Spirocyclization, bifunctional oxindole–chromone synthons, methyleneindolinones, bispirooxindole-based hexahydroxanthones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization Aza-Michael, para-quinone methide derivatives, α-bromohydroxamates, (S)-N-(benzyloxy)-2-bromo-N-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)acetamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Michael Addition Spirocyclization, substituted 2-ethylidene-1H-indene-1,3(2H)-dione, substituted bromo(nitro)methane, spironitrocyclopropanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclopropanation, Spirocyclization Cyclopropanation, 2-bromomalonates, chalcones, substituted (S)-2-carbonylcyclopropane-1,1-dicarboxylate, (9S)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeCyclopropanation Biginelli reaction, cinnamaldehydes, thiourea, b-keto-esters, 4-styryldihydropyrimidin-2-thiones, (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeBiginelli reaction, Further reactions Vinylogous Michael Addition, chalcones, α,α-Dicyanoolefins, α,α-Dicyanoolefins chalcone michael adducts, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael Addition, Vinylogous Michael Addition Cascade reaction, thiophenols, imines, chalcones, N-[(1S,2R,3S)-2-Benzoyl-3-[[4-(1,1-dimethylethyl)phenyl]thio]-1-(4-fluorophenyl)-3-(4-methylphenyl)propyl]-4-methylbenzenesulfonamide, (8α,9R)-1-[(2-nitrophenyl)methyl]-9-(2-propen-1-yloxy)- 6′-(4-propylphenyl)-cinchonanium bromide, Quinine DerivativeCascade reaction Oxa-Michael, substituted 2-(2-vinylcyclopropyl)phenol, ethyl (1S,1aS,2R,7bR)-2-(2-ethoxy-2-oxoethyl)-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael Addition, Oxa-Michael Addition« Older EntriesNext Entries »
Spirocyclization, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, α,β-unsaturated ketones, Spirocyclohexanonepyrazolones, 2-fluorobenzoic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition, Spirocyclization
Trifluoromethylthiolation, substituted 2,4-dihydro-3H-pyrazol-3-one, 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide, (R)-4-(3,5-dimethoxybenzyl)-2,5-diphenyl-4-((trifluoromethyl)thio)-2,4-dihydro-3H-pyrazol-3-one, (9S)-9-hydroxy-6′-methoxy-1-[2-oxo-2-[(triphenylmethyl)amino]ethyl]-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation
Spirocyclization, bifunctional oxindole–chromone synthons, methyleneindolinones, bispirooxindole-based hexahydroxanthones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization
Aza-Michael, para-quinone methide derivatives, α-bromohydroxamates, (S)-N-(benzyloxy)-2-bromo-N-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)acetamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Michael Addition
Spirocyclization, substituted 2-ethylidene-1H-indene-1,3(2H)-dione, substituted bromo(nitro)methane, spironitrocyclopropanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclopropanation, Spirocyclization
Cyclopropanation, 2-bromomalonates, chalcones, substituted (S)-2-carbonylcyclopropane-1,1-dicarboxylate, (9S)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeCyclopropanation
Biginelli reaction, cinnamaldehydes, thiourea, b-keto-esters, 4-styryldihydropyrimidin-2-thiones, (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeBiginelli reaction, Further reactions
Vinylogous Michael Addition, chalcones, α,α-Dicyanoolefins, α,α-Dicyanoolefins chalcone michael adducts, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael Addition, Vinylogous Michael Addition
Cascade reaction, thiophenols, imines, chalcones, N-[(1S,2R,3S)-2-Benzoyl-3-[[4-(1,1-dimethylethyl)phenyl]thio]-1-(4-fluorophenyl)-3-(4-methylphenyl)propyl]-4-methylbenzenesulfonamide, (8α,9R)-1-[(2-nitrophenyl)methyl]-9-(2-propen-1-yloxy)- 6′-(4-propylphenyl)-cinchonanium bromide, Quinine DerivativeCascade reaction
Oxa-Michael, substituted 2-(2-vinylcyclopropyl)phenol, ethyl (1S,1aS,2R,7bR)-2-(2-ethoxy-2-oxoethyl)-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-1-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael Addition, Oxa-Michael Addition
