Aza-Henry (Nitro-Mannich), substituted phenylmethanimine, substituted (nitromethyl)benzene, cis-stilbenediamines, acetic acid, Cinchonidine BaseAza-Henry, Henry, Mannich, Nitro-Mannich Sulfa-Michael Addition, β-trifluoromethyl-α,β-unsaturated ketones, thiocarboxylic acids, substituted S-(1,1,1-trifluoro-4-oxobutan-2-yl) methanethioate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Michael Addition, methyl 2-oxocyclopentane-1-carboxylate, (E)-(2-nitrovinyl)benzene, methyl (S)-1-((R)-2-nitro-1-phenylethyl)-2-oxocyclopentane-1-carboxylate, Poly[imino(3,4-dioxo-1-cyclobutene-1,2-diyl)imino[(8α,9S)-6′-methoxycinchonan-9,11-diyl]-1,4-phenylene[(8α,9S)-6′-methoxycinchonan-11,9-diyl]], Quinine DerivativeMichael, Michael Addition Oxa-Michael, N-protected 2-amino-5-(trifluoromethyl)phenol, vinyl methylene cyclic carbonates, N-protected (S)-1-(7-(trifluoromethyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)propan-2-one, tetrakis(triphenylphosphine)palladium, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAmination, Cyclization, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition Aza-Henry (Nitro-Mannich), isatin-derived N-Boc ketimines, substituted (nitromethyl)benzene, substituted tert-butyl ((R)-1-benzyl-3-((S)-nitro(phenyl)methyl)-2-oxoindolin-3-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry (Nitro-Mannich), trifluoromethyl ketimines, nitromethane, tert-butyl (S)-(1,1,1-trifluoro-3-nitro-2-substituted-propan-2-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Alkenylation, tetrahydroisoquinolines, acrylaldehyde, 2-(2-phenyl-tetrahydroisoquinolin-1-yl)acrylaldehyde, Quinine BaseAlkylation, Allylic Alkylation Aza-Michael Addition, 4-nitrobenzohydrazide, (E)-(2-nitrovinyl)benzene, (R)-4-nitro-N’-(2-nitro-1-phenylethyl)benzohydrazide, 3,4-dimethoxybenzoic acid, Quinine BaseAza-Michael, Michael Addition Sulfinylation, sodium benzenesulfinate, isopropanol, isopropyl benzenesulfinate, Quinine BaseFurther reactions, Sulfinylation Amination, 2-substituted indolin-3-ones, (E)-diazene-1,2-dicarboxylates, substituted 1-(1-acetyl-3-oxoindolin-2-yl)hydrazine-1,2-dicarboxylate, Quinine Basealpha-Amination, Amination« Older EntriesNext Entries »
Aza-Henry (Nitro-Mannich), substituted phenylmethanimine, substituted (nitromethyl)benzene, cis-stilbenediamines, acetic acid, Cinchonidine BaseAza-Henry, Henry, Mannich, Nitro-Mannich
Sulfa-Michael Addition, β-trifluoromethyl-α,β-unsaturated ketones, thiocarboxylic acids, substituted S-(1,1,1-trifluoro-4-oxobutan-2-yl) methanethioate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Michael Addition, methyl 2-oxocyclopentane-1-carboxylate, (E)-(2-nitrovinyl)benzene, methyl (S)-1-((R)-2-nitro-1-phenylethyl)-2-oxocyclopentane-1-carboxylate, Poly[imino(3,4-dioxo-1-cyclobutene-1,2-diyl)imino[(8α,9S)-6′-methoxycinchonan-9,11-diyl]-1,4-phenylene[(8α,9S)-6′-methoxycinchonan-11,9-diyl]], Quinine DerivativeMichael, Michael Addition
Oxa-Michael, N-protected 2-amino-5-(trifluoromethyl)phenol, vinyl methylene cyclic carbonates, N-protected (S)-1-(7-(trifluoromethyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)propan-2-one, tetrakis(triphenylphosphine)palladium, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAmination, Cyclization, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition
Aza-Henry (Nitro-Mannich), isatin-derived N-Boc ketimines, substituted (nitromethyl)benzene, substituted tert-butyl ((R)-1-benzyl-3-((S)-nitro(phenyl)methyl)-2-oxoindolin-3-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry (Nitro-Mannich), trifluoromethyl ketimines, nitromethane, tert-butyl (S)-(1,1,1-trifluoro-3-nitro-2-substituted-propan-2-yl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Alkenylation, tetrahydroisoquinolines, acrylaldehyde, 2-(2-phenyl-tetrahydroisoquinolin-1-yl)acrylaldehyde, Quinine BaseAlkylation, Allylic Alkylation
Aza-Michael Addition, 4-nitrobenzohydrazide, (E)-(2-nitrovinyl)benzene, (R)-4-nitro-N’-(2-nitro-1-phenylethyl)benzohydrazide, 3,4-dimethoxybenzoic acid, Quinine BaseAza-Michael, Michael Addition
Sulfinylation, sodium benzenesulfinate, isopropanol, isopropyl benzenesulfinate, Quinine BaseFurther reactions, Sulfinylation
Amination, 2-substituted indolin-3-ones, (E)-diazene-1,2-dicarboxylates, substituted 1-(1-acetyl-3-oxoindolin-2-yl)hydrazine-1,2-dicarboxylate, Quinine Basealpha-Amination, Amination
