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Bromination, 2-naphthols, N-bromophthalimide, substituted isopropyl (1R)-1-bromo-2-hydroxy-1,2-dihydronaphthalene-1-carboxylate, (9S)-9-[(4-chloro-1-phthalazinyl)oxy]-6′-methoxy-cinchonan, Quinidine Derivative

Bromination, Dearomatization, Further reactions

Amination, (1-bromoethyl)benzene, S,S-diphenylsulfoximine, (αR)-α-Methyl-N-(oxidodiphenyl-λ4-sulfanylidene)benzenemethanamine, (2-thiophenecarboxylato-κO2,κS1)-copper, 2-[bis[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]phosphino]-N-[(8α,9R)-6′-methoxycinchonan-9-yl]-benzamide, Quinidine Derivative

Amination

Spirocyclization, indoles, spirocyclic compouns, (1S,2R,4S,5R)-1-(2-bromo-5-methoxybenzyl)-2-((S)-(1-(2-bromo-5-methoxybenzyl)-6-methoxyquinolin-1-ium-4-yl)(hydroxy)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine Derivative

Spirocyclization

Cascade reaction, thioaryls, nitroolefines, carbonyl compounds, γ-sulfur-β-amino-α-hydroxy esters, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine Derivative

Cascade reaction

Cascade reaction, 2-mercaptobenzaldehyde, β,γ-unsaturated α-ketoesters, isotetronic acid-fused thiochromanes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction

Atropisomer synthesis, tert-butyl 2-(((tert-butoxycarbonyl)oxy)(phenyl)methyl)acrylate, 5-bromoquinolin-2(1H)-one, tert-butyl (Z)-3-(5-bromo-2-oxoquinolin-1(2H)-yl)-2-methyl-3-phenylacrylate, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine Derivative

Atropisomer synthesis

[2+2] Cycloaddition, cyclic ketimines, allenoates, substituted (E)-2-(8-oxo-8,8a-dihydroazeto[1,2-a]indol-2(1H)-ylidene)acetate, (9S)-6′-methoxy-9-(9-phenanthrenyloxy)-cinchonan, Quinidine Derivative

[2+2]-Cycloaddition, Cycloaddition

Spirocyclization, oxindoles, spirooxindoles, 3,4-bis[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative

Spirocyclization

Cascade reaction, α-bromonitroalkenes, 1,3-dicarbonyl compounds, tetrasubstituted 2,3-dihydrofurans, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction

Cascade reaction, 1,3-dicarbonyl derivatives, (E)-β,β-bromonitrostyrenes, dihydrofurans, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction

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