Cyclization, substituted phenylaminomaleate, substituted 2-methylenemalononitrile, chiral 1, 4-dihydropyridine derivatives, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeCyclization, Cyclization, Further Cyclizations Michael Addition, α-aryl isocyanoacetates, β-trifluoromethylated enones, substituted (3S)-2-isocyano-5-oxo-3-(trifluoromethyl)pentanoate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition Vinylogous Aldol, aldehydes, 3,4,5-trisubstituted furan-2(3H)-one, substituted 5-(hydroxymethyl)furan-2(5H)-one, N-[(2S)-2-[[2-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3-phenylpropyl]-1,1,2,2,3,3,4,4,4-nonafluoro-1-Butanesulfonamide, Dihydroquinine DerivativeAldol, Vinylogous Aldol Aza-Henry, substituted 1-benzyl-3-iminoindolinone, primary nitroalkanes, substituted (R)-3-amino-1-benzyl-3-((R)-1-nitroethyl)indolin-2-one, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-N′-[(1S)-1-hydroxy-2-phenylethyl]-thiourea, Dihydroquinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Mannich reaction, substituted 2-isocyanoacetate, 4-substituted 2-methyl-1,2,5-thiadiazol-3(2H)-one 1,1-dioxide, substituted (4S)-2-methyl-3-oxo-2,3,3a,4-tetrahydroimidazo[1,5-b][1,2,5]thiadiazole-4-carboxylate 1,1-dioxide, silver acetate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMannich, Mannich Michael Addition, nitroalkenes, S,S-diethyl propanebis(thioate), substituted S,S-diethyl 2-(2-nitroethyl)propanebis(thioate), 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition Michael Addition, α-substituted β-nitroacrylates, 1,3-dicarbonyls, ethyl (R)-3-acetyl-2-(4-methoxyphenyl)-2-(nitromethyl)-4-oxopentanoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition Vinylogous Michael Addition, ethyl (Z)-3-nitro-2-phenylacrylate, N-protected (E)-5-chloro-3-(pentan-2-ylidene)indolin-2-one, N-protected ethyl (S,Z)-4-(5-chloro-2-oxoindolin-3-ylidene)-2-(nitromethyl)-2-phenylheptanoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael Addition, Vinylogous Michael Addition Domino Michael Addition, cyclic ketones, alkylidene pyrazolones, tetrahydropyrano [2,3-c] pyrazoles, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition Spirocyclization, oxindoles, 3-chlorooxindoles, Spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCyclopropanation, Spirocyclization« Older EntriesNext Entries »
Cyclization, substituted phenylaminomaleate, substituted 2-methylenemalononitrile, chiral 1, 4-dihydropyridine derivatives, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeCyclization, Cyclization, Further Cyclizations
Michael Addition, α-aryl isocyanoacetates, β-trifluoromethylated enones, substituted (3S)-2-isocyano-5-oxo-3-(trifluoromethyl)pentanoate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition
Vinylogous Aldol, aldehydes, 3,4,5-trisubstituted furan-2(3H)-one, substituted 5-(hydroxymethyl)furan-2(5H)-one, N-[(2S)-2-[[2-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3-phenylpropyl]-1,1,2,2,3,3,4,4,4-nonafluoro-1-Butanesulfonamide, Dihydroquinine DerivativeAldol, Vinylogous Aldol
Aza-Henry, substituted 1-benzyl-3-iminoindolinone, primary nitroalkanes, substituted (R)-3-amino-1-benzyl-3-((R)-1-nitroethyl)indolin-2-one, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-N′-[(1S)-1-hydroxy-2-phenylethyl]-thiourea, Dihydroquinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Mannich reaction, substituted 2-isocyanoacetate, 4-substituted 2-methyl-1,2,5-thiadiazol-3(2H)-one 1,1-dioxide, substituted (4S)-2-methyl-3-oxo-2,3,3a,4-tetrahydroimidazo[1,5-b][1,2,5]thiadiazole-4-carboxylate 1,1-dioxide, silver acetate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMannich, Mannich
Michael Addition, nitroalkenes, S,S-diethyl propanebis(thioate), substituted S,S-diethyl 2-(2-nitroethyl)propanebis(thioate), 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition
Michael Addition, α-substituted β-nitroacrylates, 1,3-dicarbonyls, ethyl (R)-3-acetyl-2-(4-methoxyphenyl)-2-(nitromethyl)-4-oxopentanoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition
Vinylogous Michael Addition, ethyl (Z)-3-nitro-2-phenylacrylate, N-protected (E)-5-chloro-3-(pentan-2-ylidene)indolin-2-one, N-protected ethyl (S,Z)-4-(5-chloro-2-oxoindolin-3-ylidene)-2-(nitromethyl)-2-phenylheptanoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael Addition, Vinylogous Michael Addition
Domino Michael Addition, cyclic ketones, alkylidene pyrazolones, tetrahydropyrano [2,3-c] pyrazoles, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition
Spirocyclization, oxindoles, 3-chlorooxindoles, Spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCyclopropanation, Spirocyclization
