Epoxidation, β-aryl-β-trifluoromethyl-disubstituted enones, hydroperoxide, tetrasubstituted trifluoromethylated epoxides, (9S)-9-hydroxy-6′-methoxy-1-[(pentafluorophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeEpoxidation Epoxidation, β-aryl-β-trifluoromethyl-disubstituted enones, oxygen, tetrasubstituted trifluoromethylated epoxides, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeEpoxidation Cyanation, β-aryl-β-trifluoromethyl-disubstituted enones, 2-hydroxy-2-methylpropanenitrile, substituted 4-oxo-2-(trifluoromethyl)butanenitrile, (9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide, Quinidine DerivativeAddition, Cyanation Desymmetrization, aldehydes, 2,2-disubstituted propane-1,3-diol, substituted 3-hydroxypropylat, (T-4)-[tetrahydroborato(1-)-κH,κH′]bis(triphenylphosphine)-copper, 2,4,6-trichloro-N-[(9R)-6′-methoxycinchonan-9-yl]-benzenesulfonamide, Quinidine DerivativeDesymmetrization Aza-Henry (Nitro-Mannich), methyl 4-nitrobutanoate, tert-butyl (Z)-(4-chlorobenzylidene)carbamate, methyl (4S,5S)-5-((tert-butoxycarbonyl)amino)-5-(4-chlorophenyl)-4-nitropentanoate, (1S,2R,4S,5R)-1-benzyl-2-((R)-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Mannich reaction, isatin-derived ketimines, isocyanoacetates, substituted 2-((R)-3-((tert-butoxycarbonyl)amino)-2-oxoindolin-3-yl)-2-isocyanoacetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMannich, Mannich Cascade reaction, 2-mercaptoquinoline-3-carbaldehydes, nitroolefins, 3,4-Dihydro-2H-thiopyrano[2,3-b]quinolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Cascade reaction, 1,4-dithiane-2,5-diol, en-ynones, tetrahydrothiophenes, 3-[(2-Fluorophenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction Oxa-Michael, 2,6-dichlorophenyl (E)-2-diazo-4-phenylbut-3-enoate, 3-(diethylamino)phenol, 2,6-dichlorophenyl 2-((2R,3S)-6-(diethylamino)-3-phenyl-2,3-dihydrobenzofuran-2-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization« Older EntriesNext Entries »
Epoxidation, β-aryl-β-trifluoromethyl-disubstituted enones, hydroperoxide, tetrasubstituted trifluoromethylated epoxides, (9S)-9-hydroxy-6′-methoxy-1-[(pentafluorophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeEpoxidation
Epoxidation, β-aryl-β-trifluoromethyl-disubstituted enones, oxygen, tetrasubstituted trifluoromethylated epoxides, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine DerivativeEpoxidation
Cyanation, β-aryl-β-trifluoromethyl-disubstituted enones, 2-hydroxy-2-methylpropanenitrile, substituted 4-oxo-2-(trifluoromethyl)butanenitrile, (9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide, Quinidine DerivativeAddition, Cyanation
Desymmetrization, aldehydes, 2,2-disubstituted propane-1,3-diol, substituted 3-hydroxypropylat, (T-4)-[tetrahydroborato(1-)-κH,κH′]bis(triphenylphosphine)-copper, 2,4,6-trichloro-N-[(9R)-6′-methoxycinchonan-9-yl]-benzenesulfonamide, Quinidine DerivativeDesymmetrization
Aza-Henry (Nitro-Mannich), methyl 4-nitrobutanoate, tert-butyl (Z)-(4-chlorobenzylidene)carbamate, methyl (4S,5S)-5-((tert-butoxycarbonyl)amino)-5-(4-chlorophenyl)-4-nitropentanoate, (1S,2R,4S,5R)-1-benzyl-2-((R)-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Mannich reaction, isatin-derived ketimines, isocyanoacetates, substituted 2-((R)-3-((tert-butoxycarbonyl)amino)-2-oxoindolin-3-yl)-2-isocyanoacetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMannich, Mannich
Cascade reaction, 2-mercaptoquinoline-3-carbaldehydes, nitroolefins, 3,4-Dihydro-2H-thiopyrano[2,3-b]quinolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Cascade reaction, 1,4-dithiane-2,5-diol, en-ynones, tetrahydrothiophenes, 3-[(2-Fluorophenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
Oxa-Michael, 2,6-dichlorophenyl (E)-2-diazo-4-phenylbut-3-enoate, 3-(diethylamino)phenol, 2,6-dichlorophenyl 2-((2R,3S)-6-(diethylamino)-3-phenyl-2,3-dihydrobenzofuran-2-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition
Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
