Spirocyclization, 3-methyl-4-nitro-5-isatylidenyl-isoxazoles, N-2,2,2-trifluoroethylisatin ketimines, isoxazole and trifluoromethyl-containing 3,2′-pyrrolidinyl dispirooxindoles, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization Aza-Friedel-Crafts reaction, indoles, imines, (1H-indol-3-yl)(phenyl)-l3-methanamines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9S)-10,11-dihydro-6′-methoxy-11-[[3-(trihydroxysilyl)propyl]thio]cinchonan-6′-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Aza-Friedel-Crafts reaction, benzothiazolimines, 2-naphthols, 2′-aminobenzothiazolomethyl naphthols, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Cascade reaction, ethyl 2-(benzoylamino)-2-chloroacetate, 2-phenylacetyl chloride, benzylamine, ethyl (2R,3R)-2-benzamido-4-(benzylamino)-4-oxo-3-phenylbutanoate, Benzoylquinine, Quinine DerivativeCascade reaction Alkylation, tert-butyl (1-tosylpent-4-en-1-yl)carbamate, 4-fluoro-4-nitrobut-1-ene, tert-butyl ((4S,5R)-4-fluoro-4-nitronona-1,8-dien-5-yl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAlkylation, Alkylation Preparation of β-amino acids, acid chlorides, N-acyl-α-chloroglycine esters, β-substituted aspartic acid derivatives, Benzoylquinine, Quinine DerivativeFurther reactions, Preparation of β-amino acids Atropisomer synthesis, isoquinoline N-oxides, N-bromoacetamide, axially chiral isoquinoline N-oxides, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAtropisomer synthesis Dynamic kinetic resolution, 1,1,1,3,3,3-hexafluoropropan-2-yl 2-benzamido-3,3-dimethylbutanoate, (S)-2-benzamido-3,3-dimethylbutanoic acid, (8α,9R)-1-[(2-cyanophenyl)methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeDynamic Kinetic Resolution, Resolution Cascade Reaction, tert-butyl (E)-4-(3-bromophenyl)-2-methyl-4-oxobut-2-enoate, hydroxylamine, carboxy-substituted 2-isoxazolines, (1S,2R,4S,5R)-1-(2,5-bis(trifluoromethyl)benzyl)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeCascade reaction Cascade reaction, 4-mercapto-2-butenoate, 3-nitrobenzothiophenes, tetrahydrothiophenebenzothiophenes, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide, Cinchonidine DerivativeCascade reaction« Older EntriesNext Entries »
Spirocyclization, 3-methyl-4-nitro-5-isatylidenyl-isoxazoles, N-2,2,2-trifluoroethylisatin ketimines, isoxazole and trifluoromethyl-containing 3,2′-pyrrolidinyl dispirooxindoles, 3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Spirocyclization
Aza-Friedel-Crafts reaction, indoles, imines, (1H-indol-3-yl)(phenyl)-l3-methanamines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9S)-10,11-dihydro-6′-methoxy-11-[[3-(trihydroxysilyl)propyl]thio]cinchonan-6′-yl]thiourea, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Aza-Friedel-Crafts reaction, benzothiazolimines, 2-naphthols, 2′-aminobenzothiazolomethyl naphthols, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Cascade reaction, ethyl 2-(benzoylamino)-2-chloroacetate, 2-phenylacetyl chloride, benzylamine, ethyl (2R,3R)-2-benzamido-4-(benzylamino)-4-oxo-3-phenylbutanoate, Benzoylquinine, Quinine DerivativeCascade reaction
Alkylation, tert-butyl (1-tosylpent-4-en-1-yl)carbamate, 4-fluoro-4-nitrobut-1-ene, tert-butyl ((4S,5R)-4-fluoro-4-nitronona-1,8-dien-5-yl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine DerivativeAlkylation, Alkylation
Preparation of β-amino acids, acid chlorides, N-acyl-α-chloroglycine esters, β-substituted aspartic acid derivatives, Benzoylquinine, Quinine DerivativeFurther reactions, Preparation of β-amino acids
Atropisomer synthesis, isoquinoline N-oxides, N-bromoacetamide, axially chiral isoquinoline N-oxides, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine DerivativeAtropisomer synthesis
Dynamic kinetic resolution, 1,1,1,3,3,3-hexafluoropropan-2-yl 2-benzamido-3,3-dimethylbutanoate, (S)-2-benzamido-3,3-dimethylbutanoic acid, (8α,9R)-1-[(2-cyanophenyl)methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeDynamic Kinetic Resolution, Resolution
Cascade Reaction, tert-butyl (E)-4-(3-bromophenyl)-2-methyl-4-oxobut-2-enoate, hydroxylamine, carboxy-substituted 2-isoxazolines, (1S,2R,4S,5R)-1-(2,5-bis(trifluoromethyl)benzyl)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeCascade reaction
Cascade reaction, 4-mercapto-2-butenoate, 3-nitrobenzothiophenes, tetrahydrothiophenebenzothiophenes, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide, Cinchonidine DerivativeCascade reaction
