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Mannich reaction, α-aminomaleimides, N-Boc imines, β-substituted α-aminomaleimides, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-phenylurea, Quinine Derivative

Mannich, Mannich

Cyclization, α-bromonitroalkenes, 1,3-dicarbonyl compounds, 2,3-dihydrofurans, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction, Cyclization, Michael, Michael Addition

Mannich reaction, α-fluoroindanones, isatin-derived N-Boc-ketimines, 3-substituted 3-amino-2-oxindoles, 9-hydroxy-1-[(4-iodophenyl)methyl]-6′-methoxy-(8α,9R)-cinchonanium bromide, Quinine Derivative

Mannich, Mannich

Fluorination, (R)-2-methyl-N-((S,Z)-2-methyl-1-phenylbutylidene)propane-2-sulfinamide, (R)-N-((R,E)-2-fluoro-2-methyl-1-phenylbutylidene)-2-methylpropane-2-sulfinamide, (8α,9R)-1-fluoro-9-hydroxy-6′-methoxy-Cinchonanium salt with N-(phenylsulfonyl)benzenesulfonamide, Quinine Derivative

Fluorination, Fluorination

Mannich reaction, N-unprotected trifluoromethyl ketimines, diketones, N-unprotected α-tetrasubstituted amino acid esters, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael, Michael Addition

Resolution, 3-phenyloxetan-2-one, OH-donors, (S)-3-hydroxy-2-phenylpropanoic acid, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-(9S)-cinchonanium chloride, Quinidine Derivative

Dynamic Kinetic Resolution, Resolution

Michael Addition, 1,3-diaryl-1,3-propanedione, nitroolefins, 1,3-diaryl-(2R)-nitroolefin-1,3-propanediones, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative

Michael, Michael Addition

Michael Addition, bis-oxindoles, nitroethene, nitroalkylated bis-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine Derivative

Michael, Michael Addition

Michael Addition, α-branched nitroalkanes, α′-hydroxy enone, tertiary nitrocompounds, 9-Anthracenylmethyl N-[(1S)-1-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Quinine Derivative

Michael, Michael Addition

Cascade reaction, (E)-2-(2-nitrovinyl)phenol, methyl 2-oxocyclopentane-1-carboxylate, chiral benzopyrans, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction, Michael, Michael Addition, Spirocyclization

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