Spirocyclization, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, substituted (E)-4-benzylidene-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, trifluoromethyl-containing spiro-pyrrolidine-pyrazolone compounds, 3-[[(9R)-6′-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative1,3-Dipolar Cycloaddition, Cycloaddition, Spirocyclization Michael Addition, 1-Benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-4H-imidazol-4-one, 2-Benzylidene-1,3-benzodithiole 1,1,3,3-tetroxide, (5S)-1-benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-5-[(R)-phenyl(1,1,3,3-tetraoxido-2H-1,3-benzodithiol-2-yl)methyl]-4H-Imidazol-4-one, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, Quinine DerivativeMichael, Michael Addition intramolecular Oxa-Michael, alkoxyboronates, 1-substituted isochromanes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition Spirocyclization, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, α,β-unsaturated ketones, Spirocyclohexanonepyrazolones, 2-fluorobenzoic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition, Spirocyclization Trifluoromethylthiolation, substituted 2,4-dihydro-3H-pyrazol-3-one, 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide, (R)-4-(3,5-dimethoxybenzyl)-2,5-diphenyl-4-((trifluoromethyl)thio)-2,4-dihydro-3H-pyrazol-3-one, (9S)-9-hydroxy-6′-methoxy-1-[2-oxo-2-[(triphenylmethyl)amino]ethyl]-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation Spirocyclization, bifunctional oxindole–chromone synthons, methyleneindolinones, bispirooxindole-based hexahydroxanthones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization Aza-Michael, para-quinone methide derivatives, α-bromohydroxamates, (S)-N-(benzyloxy)-2-bromo-N-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)acetamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Michael Addition Spirocyclization, substituted 2-ethylidene-1H-indene-1,3(2H)-dione, substituted bromo(nitro)methane, spironitrocyclopropanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclopropanation, Spirocyclization Cyclopropanation, 2-bromomalonates, chalcones, substituted (S)-2-carbonylcyclopropane-1,1-dicarboxylate, (9S)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeCyclopropanation Biginelli reaction, cinnamaldehydes, thiourea, b-keto-esters, 4-styryldihydropyrimidin-2-thiones, (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeBiginelli reaction, Further reactions« Older EntriesNext Entries »
Spirocyclization, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, substituted (E)-4-benzylidene-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, trifluoromethyl-containing spiro-pyrrolidine-pyrazolone compounds, 3-[[(9R)-6′-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative1,3-Dipolar Cycloaddition, Cycloaddition, Spirocyclization
Michael Addition, 1-Benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-4H-imidazol-4-one, 2-Benzylidene-1,3-benzodithiole 1,1,3,3-tetroxide, (5S)-1-benzoyl-1,5-dihydro-5-(phenylmethyl)-2-[(phenylmethyl)thio]-5-[(R)-phenyl(1,1,3,3-tetraoxido-2H-1,3-benzodithiol-2-yl)methyl]-4H-Imidazol-4-one, N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-5-(trifluoromethyl)benzamide, Quinine DerivativeMichael, Michael Addition
intramolecular Oxa-Michael, alkoxyboronates, 1-substituted isochromanes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivativeintramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition
Spirocyclization, substituted 4-methylene-2,4-dihydro-3H-pyrazol-3-one, α,β-unsaturated ketones, Spirocyclohexanonepyrazolones, 2-fluorobenzoic acid, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition, Spirocyclization
Trifluoromethylthiolation, substituted 2,4-dihydro-3H-pyrazol-3-one, 2-((trifluoromethyl)thio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide, (R)-4-(3,5-dimethoxybenzyl)-2,5-diphenyl-4-((trifluoromethyl)thio)-2,4-dihydro-3H-pyrazol-3-one, (9S)-9-hydroxy-6′-methoxy-1-[2-oxo-2-[(triphenylmethyl)amino]ethyl]-cinchonanium bromide, Quinidine DerivativeTrifluoro-methylthiolation
Spirocyclization, bifunctional oxindole–chromone synthons, methyleneindolinones, bispirooxindole-based hexahydroxanthones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization
Aza-Michael, para-quinone methide derivatives, α-bromohydroxamates, (S)-N-(benzyloxy)-2-bromo-N-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)acetamide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeAza-Michael, Michael Addition
Spirocyclization, substituted 2-ethylidene-1H-indene-1,3(2H)-dione, substituted bromo(nitro)methane, spironitrocyclopropanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclopropanation, Spirocyclization
Cyclopropanation, 2-bromomalonates, chalcones, substituted (S)-2-carbonylcyclopropane-1,1-dicarboxylate, (9S)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinidine DerivativeCyclopropanation
Biginelli reaction, cinnamaldehydes, thiourea, b-keto-esters, 4-styryldihydropyrimidin-2-thiones, (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeBiginelli reaction, Further reactions
