Desymmetrization, aldehydes, 2,2-disubstituted propane-1,3-diol, substituted 3-hydroxypropylat, (T-4)-[tetrahydroborato(1-)-κH,κH′]bis(triphenylphosphine)-copper, 2,4,6-trichloro-N-[(9R)-6′-methoxycinchonan-9-yl]-benzenesulfonamide, Quinidine DerivativeDesymmetrization Aza-Henry (Nitro-Mannich), methyl 4-nitrobutanoate, tert-butyl (Z)-(4-chlorobenzylidene)carbamate, methyl (4S,5S)-5-((tert-butoxycarbonyl)amino)-5-(4-chlorophenyl)-4-nitropentanoate, (1S,2R,4S,5R)-1-benzyl-2-((R)-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Mannich reaction, isatin-derived ketimines, isocyanoacetates, substituted 2-((R)-3-((tert-butoxycarbonyl)amino)-2-oxoindolin-3-yl)-2-isocyanoacetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMannich, Mannich Cascade reaction, 2-mercaptoquinoline-3-carbaldehydes, nitroolefins, 3,4-Dihydro-2H-thiopyrano[2,3-b]quinolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Cascade reaction, 1,4-dithiane-2,5-diol, en-ynones, tetrahydrothiophenes, 3-[(2-Fluorophenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction Oxa-Michael, 2,6-dichlorophenyl (E)-2-diazo-4-phenylbut-3-enoate, 3-(diethylamino)phenol, 2,6-dichlorophenyl 2-((2R,3S)-6-(diethylamino)-3-phenyl-2,3-dihydrobenzofuran-2-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Spirocyclization, methyl (E)-2-(1-methyl-2-oxoindolin-3-ylidene)acetate, 7-methyl-3-((2,2,2-trifluoroethyl)imino)benzo[b]thiophen-2(3H)-one, bispiro[oxindole‐pyrrolidine‐benzothiophenone]s, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeSpirocyclization Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Spirocyclization, substituted 5-methyl-4-methylene-2,4-dihydro-3H-pyrazol-3-one, substituted (E)-2-((2,2-difluoroethyl)imino)benzo[b]thiophen-3(2H)-one, CF2H-containing dispiro [benzo[b]thiophene-pyrrolidine-pyrazole]s, N-[(9R)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-thiourea, Quinidine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization« Older EntriesNext Entries »
Desymmetrization, aldehydes, 2,2-disubstituted propane-1,3-diol, substituted 3-hydroxypropylat, (T-4)-[tetrahydroborato(1-)-κH,κH′]bis(triphenylphosphine)-copper, 2,4,6-trichloro-N-[(9R)-6′-methoxycinchonan-9-yl]-benzenesulfonamide, Quinidine DerivativeDesymmetrization
Aza-Henry (Nitro-Mannich), methyl 4-nitrobutanoate, tert-butyl (Z)-(4-chlorobenzylidene)carbamate, methyl (4S,5S)-5-((tert-butoxycarbonyl)amino)-5-(4-chlorophenyl)-4-nitropentanoate, (1S,2R,4S,5R)-1-benzyl-2-((R)-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Mannich reaction, isatin-derived ketimines, isocyanoacetates, substituted 2-((R)-3-((tert-butoxycarbonyl)amino)-2-oxoindolin-3-yl)-2-isocyanoacetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMannich, Mannich
Cascade reaction, 2-mercaptoquinoline-3-carbaldehydes, nitroolefins, 3,4-Dihydro-2H-thiopyrano[2,3-b]quinolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Cascade reaction, 1,4-dithiane-2,5-diol, en-ynones, tetrahydrothiophenes, 3-[(2-Fluorophenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeCascade reaction
Oxa-Michael, 2,6-dichlorophenyl (E)-2-diazo-4-phenylbut-3-enoate, 3-(diethylamino)phenol, 2,6-dichlorophenyl 2-((2R,3S)-6-(diethylamino)-3-phenyl-2,3-dihydrobenzofuran-2-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Michael Addition, Oxa-Michael Addition
Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Spirocyclization, methyl (E)-2-(1-methyl-2-oxoindolin-3-ylidene)acetate, 7-methyl-3-((2,2,2-trifluoroethyl)imino)benzo[b]thiophen-2(3H)-one, bispiro[oxindole‐pyrrolidine‐benzothiophenone]s, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeSpirocyclization
Spirocyclization, unsaturated pyrrolin-4-ones, 2-mercaptoacetaldehyde, spiro-Δ2-pyrrolin-4-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Spirocyclization, substituted 5-methyl-4-methylene-2,4-dihydro-3H-pyrazol-3-one, substituted (E)-2-((2,2-difluoroethyl)imino)benzo[b]thiophen-3(2H)-one, CF2H-containing dispiro [benzo[b]thiophene-pyrrolidine-pyrazole]s, N-[(9R)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-thiourea, Quinidine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization
