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Cascade reaction, ethyl 2-(benzoylamino)-2-chloroacetate, 2-phenylacetyl chloride, benzylamine, ethyl (2R,3R)-2-benzamido-4-(benzylamino)-4-oxo-3-phenylbutanoate, Benzoylquinine, Quinine Derivative

Cascade reaction

Alkylation, tert-butyl (1-tosylpent-4-en-1-yl)carbamate, 4-fluoro-4-nitrobut-1-ene, tert-butyl ((4S,5R)-4-fluoro-4-nitronona-1,8-dien-5-yl)carbamate, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium chloride, Quinine Derivative

Alkylation, Alkylation

Preparation of β-amino acids, acid chlorides, N-acyl-α-chloroglycine esters, β-substituted aspartic acid derivatives, Benzoylquinine, Quinine Derivative

Further reactions, Preparation of β-amino acids

Atropisomer synthesis, isoquinoline N-oxides, N-bromoacetamide, axially chiral isoquinoline N-oxides, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine Derivative

Atropisomer synthesis

Dynamic kinetic resolution, 1,1,1,3,3,3-hexafluoropropan-2-yl 2-benzamido-3,3-dimethylbutanoate, (S)-2-benzamido-3,3-dimethylbutanoic acid, (8α,9R)-1-[(2-cyanophenyl)methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine Derivative

Dynamic Kinetic Resolution, Resolution

Cascade Reaction, tert-butyl (E)-4-(3-bromophenyl)-2-methyl-4-oxobut-2-enoate, hydroxylamine, carboxy-substituted 2-isoxazolines, (1S,2R,4S,5R)-1-(2,5-bis(trifluoromethyl)benzyl)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine Derivative

Cascade reaction

Cascade reaction, 4-mercapto-2-butenoate, 3-nitrobenzothiophenes, tetrahydrothiophenebenzothiophenes, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide, Cinchonidine Derivative

Cascade reaction

Epoxidation, β-aryl-β-trifluoromethyl-disubstituted enones, hydroperoxide, tetrasubstituted trifluoromethylated epoxides, (9S)-9-hydroxy-6′-methoxy-1-[(pentafluorophenyl)methyl]-cinchonanium bromide, Quinidine Derivative

Epoxidation

Epoxidation, β-aryl-β-trifluoromethyl-disubstituted enones, oxygen, tetrasubstituted trifluoromethylated epoxides, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine Derivative

Epoxidation

Cyanation, β-aryl-β-trifluoromethyl-disubstituted enones, 2-hydroxy-2-methylpropanenitrile, substituted 4-oxo-2-(trifluoromethyl)butanenitrile, (9S)-1-[[2,5-bis(trifluoromethyl)phenyl]methyl]-6′,9-dimethoxy-cinchonanium bromide, Quinidine Derivative

Addition, Cyanation

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