Flow Chemistry, spiro[cyclohexane-1,3′-indole], ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeFlow Chemistry, Strecker Desymmetrization, unprotected sulfonimidamides, 2,2,2-trifluoroethyl 2,2,2-trifluoroacetate, enantioenriched sulfonimidamides, (8α,9R)-6′-methoxy-Cinchonan-9-ol-9-(P,P-dicyclohexylphosphinate), Quinine DerivativeAcylation, Desymmetrization [4+2]-Cycloaddition, 2-Amino-β-nitrostyrenes, Cyclic N-Sulfonyl Ketimines, Polycyclic Benzosultams, 2-[[3,4-dioxo-2-[[(1S)-1-phenylethyl]amino]-1-cyclobuten-1-yl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-(2S)-butanamide, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition Resolution, 3-phenyloxetan-2-one, (S)-3-hydroxy-2-phenylpropanoic acid, (R)-3-hydroxy-2-phenylpropanoic acid, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-(9S)-Cinchonanium chloride, Quinidine DerivativeDynamic Kinetic Resolution, Resolution Racemic Resolution, racemic 7-bromo-3-oxo-4-phenyl-2-oxabicyclo[2.2.2]oct-7-ene-5-carboxylic acid, 7-bromo-3-oxo-4-phenyl-2-oxabicyclo[2.2.2]oct-7-ene-5-carboxylic acid, Quinidine BaseRacemic resolution, Resolution Rearrangement, substituted 1-mercapto-2-oxopropyl acetate, α‐acyloxy thioesters, Quinidine BaseFurther reactions, Rearrangement Atropisomer Synthesis, ethyl 4-benzoyl-1-((methoxycarbonyl)amino)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylate, benzyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, ethyl 4-benzoyl-1-((2-((benzyloxy)carbonyl)allyl)(methoxycarbonyl)amino)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylate, Quinidine BaseAtropisomer synthesis Racemic Resolution, racemic sodium 2′-(dicyclohexylphosphaneyl)-2,6-dimethoxy-[1,1′-biphenyl]-3-sulfonate, sodium (R)-2′-(dicyclohexylphosphaneyl)-2,6-dimethoxy-[1,1′-biphenyl]-3-sulfonate, Quinidine BaseRacemic resolution, Resolution Cycloaddition, ethyl 2,3-butadienoate, substituted trifluorobut-3-en-2-one, 6-trifluoromethyl‐substituted dihydropyrans, Quinidine Base[4+2]-Cycloaddition, Cycloaddition Spirocyclization, isoindigos, 1,4-dithiane-2,5-diol, bispirooxindole tetrahydrothiophenes, Quinidine BaseSpirocyclization« Older EntriesNext Entries »
Flow Chemistry, spiro[cyclohexane-1,3′-indole], ethyl carbonocyanidate, (S)-spiro[cyclohexane-1,3′-indoline]-2′-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeFlow Chemistry, Strecker
Desymmetrization, unprotected sulfonimidamides, 2,2,2-trifluoroethyl 2,2,2-trifluoroacetate, enantioenriched sulfonimidamides, (8α,9R)-6′-methoxy-Cinchonan-9-ol-9-(P,P-dicyclohexylphosphinate), Quinine DerivativeAcylation, Desymmetrization
[4+2]-Cycloaddition, 2-Amino-β-nitrostyrenes, Cyclic N-Sulfonyl Ketimines, Polycyclic Benzosultams, 2-[[3,4-dioxo-2-[[(1S)-1-phenylethyl]amino]-1-cyclobuten-1-yl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-(2S)-butanamide, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition
Resolution, 3-phenyloxetan-2-one, (S)-3-hydroxy-2-phenylpropanoic acid, (R)-3-hydroxy-2-phenylpropanoic acid, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-(9S)-Cinchonanium chloride, Quinidine DerivativeDynamic Kinetic Resolution, Resolution
Racemic Resolution, racemic 7-bromo-3-oxo-4-phenyl-2-oxabicyclo[2.2.2]oct-7-ene-5-carboxylic acid, 7-bromo-3-oxo-4-phenyl-2-oxabicyclo[2.2.2]oct-7-ene-5-carboxylic acid, Quinidine BaseRacemic resolution, Resolution
Rearrangement, substituted 1-mercapto-2-oxopropyl acetate, α‐acyloxy thioesters, Quinidine BaseFurther reactions, Rearrangement
Atropisomer Synthesis, ethyl 4-benzoyl-1-((methoxycarbonyl)amino)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylate, benzyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, ethyl 4-benzoyl-1-((2-((benzyloxy)carbonyl)allyl)(methoxycarbonyl)amino)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylate, Quinidine BaseAtropisomer synthesis
Racemic Resolution, racemic sodium 2′-(dicyclohexylphosphaneyl)-2,6-dimethoxy-[1,1′-biphenyl]-3-sulfonate, sodium (R)-2′-(dicyclohexylphosphaneyl)-2,6-dimethoxy-[1,1′-biphenyl]-3-sulfonate, Quinidine BaseRacemic resolution, Resolution
Cycloaddition, ethyl 2,3-butadienoate, substituted trifluorobut-3-en-2-one, 6-trifluoromethyl‐substituted dihydropyrans, Quinidine Base[4+2]-Cycloaddition, Cycloaddition
Spirocyclization, isoindigos, 1,4-dithiane-2,5-diol, bispirooxindole tetrahydrothiophenes, Quinidine BaseSpirocyclization
