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[10+2]-Cycloaddition, 2-alkylidene-1-indanones, activated alkenes, polyhydrocyclopenta[a]indene frameworks with multiple functionalities, 9-hydroxy-6′-methoxy-1-[[2,4,6-tris(1-methylethyl)phenyl]methyl]-(8α,9R)-cinchonanium bromide, Quinine Derivative

[10+2]-Cycloaddition, Cycloaddition

Cascade reaction, cyclobutanone carbon esters, ortho-quinone methides, 8-membered lactone derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction, Cyclization, Lactonization

Michael Addition, 4-hydroxycoumarin, (E)-(2-nitrovinyl)benzene, (R)-4-hydroxy-3-(2-nitro-1-phenylethyl)-2H-chromen-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Michael, Michael Addition

[4+1]-Annulation, N-(2-(chloromethyl)phenyl)-4-methylbenzenesulfonamide, 4-bromo-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, (R)-3′-methyl-1′-phenyl-1-tosylspiro[indoline-2,4′-pyrazol]-5′(1’H)-one, 3,4-bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

[4+1]-Annulation, Cyclization, Further Cyclizations, Spirocyclization

Cascade reaction, ortho-aromatic diamines, unsaturated dicarbonyl compounds, chiral fused benzimidazoles, 3-[(2-hydroxyphenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction

Cross-Coupling, tertiary alkyl bromides, organoboronate esters, α-quaternary chiral β-lactams, N-[(9S)-6′-methoxycinchonan-9-yl]-2-(1-methylethyl)-8-quinolinesulfonamide, Quinine Derivative

Cross Coupling

Cross-Coupling, alkyl halides, alkenylboronate esters, enantioenriched alkenes, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-2-methyl-8-quinolinesulfonamide, Quinine Derivative

Cross Coupling

Atropisomer Synthesis, pyrroles, benzhydryl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, atropisomers, Quinidine Base

Atropisomer synthesis

Aldol reaction, isatins, 3‐Acetyl‐2H‐chromen‐2‐ones, substituted (R)-3-hydroxy-3-(2-oxo-2-(2-oxo-2H-chromen-3-yl)ethyl)indolin-2-one, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-urea, Quinidine Derivative

Aldol, Aldol

Oxa-Michael Addition, (E)-6-hydroxy-1-phenylhex-2-en-1-one, (R)-1-phenyl-2-(tetrahydrofuran-2-yl)ethan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition

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