Spirocyclization, N-protected [3,3′-biindoline]-2,2′-dione, formaldehyde, N-protected (3R)-4-(2-aminophenyl)-2H-spiro[furan-3,3′-indoline]-2′,5(4H)-dione, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAldol, Aldol, Spirocyclization Spirocyclization, N-2,2,2-trifluoroethylisatin ketimines, unsymmetrical dicarbonyl-activated alkenes, 5′-trifluoromethylated 3,2′-pyrrolidinyl spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeSpirocyclization Michael Addition, oxazol-5-(4H)-ones, β-nitroacrylates, 4,4-disubstituted oxazol-5-(4H)-ones, N-(9R)-cinchonan-9-yl-8-quinolinesulfonamide, Cinchonine DerivativeMichael, Michael Addition Atropisomer Synthesis, biaryl lactones, ethyl 2-cyanoacetate, atropisomer, silver carbonate, N-(9R)-cinchonan-9-yl-2-(diphenylphosphino)-benzamide, Cinchonine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution Alkylation, β-ketoesters, iodoalkanes, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylates, (9S)-9-hydroxy-2′-[4-(trifluoromethyl)phenyl]-1-[(3,4,5-trifluorophenyl)methyl]-cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation Alkylation, sulfenamides, benzyl iodide, (R,E)-N-(benzyl(phenyl)-λ4-sulfaneylidene)-2,2-diethylbutanamide, (9S)-9-hydroxy-1-(phenylmethyl)-cinchonanium chloride, Cinchonine DerivativeAlkylation, Alkylation, S-Alkylation Aziridination, substituted oxazolones, 2-azidoacrylates, aziridines, N-(9R)-cinchonan-9-yl-8-quinolinesulfonamide, Cinchonine DerivativeAziridination Spirocyclization, unsaturated pyrazolones, 1,3‐diketones, spiropyrazolones, 3-[(9R)-cinchonan-9-ylamino]-4-[(phenylmethyl)amino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition, Spirocyclization Hydrogenation, ketones, hydrogen, substituted benzyl alcohol, Grubbs’ catalyst, (9R)-N-pentyl-cinchonan-9-amine, Cinchonine DerivativeHydrogenation, Hydrogenation of ketones Cyclization, nitroalkenes, ethyl (E)-5-(benzylamino)pent-2-enoate, substituted ethyl 2-((3S)-1-benzyl-3-nitropiperidin-4-yl)acetate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Michael Addition« Older EntriesNext Entries »
Spirocyclization, N-protected [3,3′-biindoline]-2,2′-dione, formaldehyde, N-protected (3R)-4-(2-aminophenyl)-2H-spiro[furan-3,3′-indoline]-2′,5(4H)-dione, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAldol, Aldol, Spirocyclization
Spirocyclization, N-2,2,2-trifluoroethylisatin ketimines, unsymmetrical dicarbonyl-activated alkenes, 5′-trifluoromethylated 3,2′-pyrrolidinyl spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeSpirocyclization
Michael Addition, oxazol-5-(4H)-ones, β-nitroacrylates, 4,4-disubstituted oxazol-5-(4H)-ones, N-(9R)-cinchonan-9-yl-8-quinolinesulfonamide, Cinchonine DerivativeMichael, Michael Addition
Atropisomer Synthesis, biaryl lactones, ethyl 2-cyanoacetate, atropisomer, silver carbonate, N-(9R)-cinchonan-9-yl-2-(diphenylphosphino)-benzamide, Cinchonine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution
Alkylation, β-ketoesters, iodoalkanes, substituted 1-oxo-2,3-dihydro-1H-indene-2-carboxylates, (9S)-9-hydroxy-2′-[4-(trifluoromethyl)phenyl]-1-[(3,4,5-trifluorophenyl)methyl]-cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation
Alkylation, sulfenamides, benzyl iodide, (R,E)-N-(benzyl(phenyl)-λ4-sulfaneylidene)-2,2-diethylbutanamide, (9S)-9-hydroxy-1-(phenylmethyl)-cinchonanium chloride, Cinchonine DerivativeAlkylation, Alkylation, S-Alkylation
Aziridination, substituted oxazolones, 2-azidoacrylates, aziridines, N-(9R)-cinchonan-9-yl-8-quinolinesulfonamide, Cinchonine DerivativeAziridination
Spirocyclization, unsaturated pyrazolones, 1,3‐diketones, spiropyrazolones, 3-[(9R)-cinchonan-9-ylamino]-4-[(phenylmethyl)amino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition, Spirocyclization
Hydrogenation, ketones, hydrogen, substituted benzyl alcohol, Grubbs’ catalyst, (9R)-N-pentyl-cinchonan-9-amine, Cinchonine DerivativeHydrogenation, Hydrogenation of ketones
Cyclization, nitroalkenes, ethyl (E)-5-(benzylamino)pent-2-enoate, substituted ethyl 2-((3S)-1-benzyl-3-nitropiperidin-4-yl)acetate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Michael Addition
