Atropisomer Synthesis, substituted (1H-pyrrol-1-yl)carbamate, O-protected tert-butyl 2-(hydroxymethyl)acrylate, N–N atropisomer, Quinidine BaseAtropisomer synthesis Dimerization of ketenes, butyryl chloride, N,O-dimethylhydroxylamine, (S)-2-ethyl-N-methoxy-N-methyl-3-oxohexanamide, (9S)-6′-methoxy-9-(2-propyn-1-yloxy)-cinchonan, Quinidine DerivativeDimerization, Further reactions Cycloaddition, cyclohept-2-enone, ethyl 2-cyano-2-(cyclohepta-2,4,6-trien-1-ylidene)acetate, tricyclic compound, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[8+2]-Cycloaddition, Cycloaddition Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-L-phenylalaninate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation Spirocyclization, 3‐hydroxychromenones, isatylidenemalononitriles, (S)-2-amino-5′-bromo-1′-methyl-2′,10-dioxo-5,10-dihydrospiro[benzo[g]chromene-4,3′-indoline]-3-carbonitrile, 3-(((3S,5S,7S)-adamantan-1-yl)amino)-4-(((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Quinidine DerivativeMichael, Michael Addition, Spirocyclization Decarboxylative Mannich, N-cyano imines, malonic acid half thioesters, substituted 3-cyanamidopropanethioate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMannich, Mannich cascade reaction, α,β-unsaturated ketones, trifluoro-3-oxobutanoates, trifluoromethyl substituted cyclohexanones, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAldol, Aldol, Cascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition Sulfenylation, deconjugated butyrolactams, substituted 1-mercaptopyrrolidine-2,5-dione, substituted 1-selenopyrrolidine-2,5-dione, chiral butyrolactams, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation Addition, kojic acid derivatives, β-nitroolefins, 6-(((tert-butyldimethylsilyl)oxy)methyl)-3-hydroxy-2-(2-nitro-1-phenylethyl)-4H-pyran-4-one, (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(3-((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)tetrahydro-2H-pyran-3,4,5-triyl triacetate, Quinidine DerivativeAddition Spirocyclization, oxindoles, (E)-4-mercaptobut-2-enoates, spirocyclic oxindoles, (1S,2R,4S,5R)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((10-phenylanthracen-9-yl)methyl)-5-vinylquinuclidin-1-ium chloride, Quinidine DerivativeMichael Addition, Spirocyclization, Sulfa-Michael, Sulfa-Michael Addition« Older EntriesNext Entries »
Atropisomer Synthesis, substituted (1H-pyrrol-1-yl)carbamate, O-protected tert-butyl 2-(hydroxymethyl)acrylate, N–N atropisomer, Quinidine BaseAtropisomer synthesis
Dimerization of ketenes, butyryl chloride, N,O-dimethylhydroxylamine, (S)-2-ethyl-N-methoxy-N-methyl-3-oxohexanamide, (9S)-6′-methoxy-9-(2-propyn-1-yloxy)-cinchonan, Quinidine DerivativeDimerization, Further reactions
Cycloaddition, cyclohept-2-enone, ethyl 2-cyano-2-(cyclohepta-2,4,6-trien-1-ylidene)acetate, tricyclic compound, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[8+2]-Cycloaddition, Cycloaddition
Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-L-phenylalaninate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation
Spirocyclization, 3‐hydroxychromenones, isatylidenemalononitriles, (S)-2-amino-5′-bromo-1′-methyl-2′,10-dioxo-5,10-dihydrospiro[benzo[g]chromene-4,3′-indoline]-3-carbonitrile, 3-(((3S,5S,7S)-adamantan-1-yl)amino)-4-(((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Quinidine DerivativeMichael, Michael Addition, Spirocyclization
Decarboxylative Mannich, N-cyano imines, malonic acid half thioesters, substituted 3-cyanamidopropanethioate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMannich, Mannich
cascade reaction, α,β-unsaturated ketones, trifluoro-3-oxobutanoates, trifluoromethyl substituted cyclohexanones, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAldol, Aldol, Cascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition
Sulfenylation, deconjugated butyrolactams, substituted 1-mercaptopyrrolidine-2,5-dione, substituted 1-selenopyrrolidine-2,5-dione, chiral butyrolactams, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation
Addition, kojic acid derivatives, β-nitroolefins, 6-(((tert-butyldimethylsilyl)oxy)methyl)-3-hydroxy-2-(2-nitro-1-phenylethyl)-4H-pyran-4-one, (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(3-((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)tetrahydro-2H-pyran-3,4,5-triyl triacetate, Quinidine DerivativeAddition
Spirocyclization, oxindoles, (E)-4-mercaptobut-2-enoates, spirocyclic oxindoles, (1S,2R,4S,5R)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((10-phenylanthracen-9-yl)methyl)-5-vinylquinuclidin-1-ium chloride, Quinidine DerivativeMichael Addition, Spirocyclization, Sulfa-Michael, Sulfa-Michael Addition
