Hydrogenation, ketones, hydrogen, substituted benzyl alcohol, Grubbs’ catalyst, (9R)-N-pentyl-cinchonan-9-amine, Cinchonine DerivativeHydrogenation, Hydrogenation of ketones Cyclization, nitroalkenes, ethyl (E)-5-(benzylamino)pent-2-enoate, substituted ethyl 2-((3S)-1-benzyl-3-nitropiperidin-4-yl)acetate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Michael Addition Cycloaddition, benzothiazoles, nitroenynes, ethyl (2R,3S)-1-((E)-benzylidene)-2-nitro-3-(thiophen-2-yl)-2,3-dihydro-1H-benzo[4,5]thiazolo[3,2-a]pyridine-4-carboxylate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine Derivative[3+3]-Cycloaddition, Cycloaddition Michael Addition, 2-chloroacrylonitrile, S-methyl 2-cyanopropanethioate, S-methyl (2S,4R)-4-chloro-2,4-dicyano-2-methylbutanethioate, (9S)-9-acetate-cinchonan-6′,9-diol, Cupreidine DerivativeMichael, Michael Addition Dihydroxylation, (E)-3-methyl-5-phenylpent-2-enoates, potassium permanganate, (2S,3R)-2,3-dihydroxy-3-methyl-5-phenylpentanoates, (9S)-1-[[5-bromo-3′,5′-bis(trifluoromethyl)[1,1′-biphenyl]-3-yl]methyl]-9-[[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]methoxy]-cinchonanium bromide, Cinchonine Derivative Atropisomer Synthesis, substituted (1H-pyrrol-1-yl)carbamate, O-protected tert-butyl 2-(hydroxymethyl)acrylate, N–N atropisomer, Quinidine BaseAtropisomer synthesis Dimerization of ketenes, butyryl chloride, N,O-dimethylhydroxylamine, (S)-2-ethyl-N-methoxy-N-methyl-3-oxohexanamide, (9S)-6′-methoxy-9-(2-propyn-1-yloxy)-cinchonan, Quinidine DerivativeDimerization, Further reactions Cycloaddition, cyclohept-2-enone, ethyl 2-cyano-2-(cyclohepta-2,4,6-trien-1-ylidene)acetate, tricyclic compound, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[8+2]-Cycloaddition, Cycloaddition Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-L-phenylalaninate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation Spirocyclization, 3‐hydroxychromenones, isatylidenemalononitriles, (S)-2-amino-5′-bromo-1′-methyl-2′,10-dioxo-5,10-dihydrospiro[benzo[g]chromene-4,3′-indoline]-3-carbonitrile, 3-(((3S,5S,7S)-adamantan-1-yl)amino)-4-(((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Quinidine DerivativeMichael, Michael Addition, Spirocyclization« Older EntriesNext Entries »
Hydrogenation, ketones, hydrogen, substituted benzyl alcohol, Grubbs’ catalyst, (9R)-N-pentyl-cinchonan-9-amine, Cinchonine DerivativeHydrogenation, Hydrogenation of ketones
Cyclization, nitroalkenes, ethyl (E)-5-(benzylamino)pent-2-enoate, substituted ethyl 2-((3S)-1-benzyl-3-nitropiperidin-4-yl)acetate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAza-Michael, Cyclization, Cyclization, Further Cyclizations, Michael Addition
Cycloaddition, benzothiazoles, nitroenynes, ethyl (2R,3S)-1-((E)-benzylidene)-2-nitro-3-(thiophen-2-yl)-2,3-dihydro-1H-benzo[4,5]thiazolo[3,2-a]pyridine-4-carboxylate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine Derivative[3+3]-Cycloaddition, Cycloaddition
Michael Addition, 2-chloroacrylonitrile, S-methyl 2-cyanopropanethioate, S-methyl (2S,4R)-4-chloro-2,4-dicyano-2-methylbutanethioate, (9S)-9-acetate-cinchonan-6′,9-diol, Cupreidine DerivativeMichael, Michael Addition
Dihydroxylation, (E)-3-methyl-5-phenylpent-2-enoates, potassium permanganate, (2S,3R)-2,3-dihydroxy-3-methyl-5-phenylpentanoates, (9S)-1-[[5-bromo-3′,5′-bis(trifluoromethyl)[1,1′-biphenyl]-3-yl]methyl]-9-[[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]methoxy]-cinchonanium bromide, Cinchonine Derivative
Atropisomer Synthesis, substituted (1H-pyrrol-1-yl)carbamate, O-protected tert-butyl 2-(hydroxymethyl)acrylate, N–N atropisomer, Quinidine BaseAtropisomer synthesis
Dimerization of ketenes, butyryl chloride, N,O-dimethylhydroxylamine, (S)-2-ethyl-N-methoxy-N-methyl-3-oxohexanamide, (9S)-6′-methoxy-9-(2-propyn-1-yloxy)-cinchonan, Quinidine DerivativeDimerization, Further reactions
Cycloaddition, cyclohept-2-enone, ethyl 2-cyano-2-(cyclohepta-2,4,6-trien-1-ylidene)acetate, tricyclic compound, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[8+2]-Cycloaddition, Cycloaddition
Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-L-phenylalaninate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation
Spirocyclization, 3‐hydroxychromenones, isatylidenemalononitriles, (S)-2-amino-5′-bromo-1′-methyl-2′,10-dioxo-5,10-dihydrospiro[benzo[g]chromene-4,3′-indoline]-3-carbonitrile, 3-(((3S,5S,7S)-adamantan-1-yl)amino)-4-(((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Quinidine DerivativeMichael, Michael Addition, Spirocyclization
