Trifluoromethylation, alkynyl ketones, trimethylsilyl trifluoromethane, trifluoromethylated alkynyl alcohols, (9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[9-hydroxy-cinchonanium bromide (1:2), Cinchonine DerivativeFluorination, Fluoromethylation, Trifluoromethylation Aldol reaction, substituted 3-(2-aminoethyl)indolin-2-one, formaldehyde, substituted (S)-3-(2-aminoethyl)-3-(hydroxymethyl)indolin-2-one, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAldol, Aldol Addition, isatins, α‐amido malonic acid half oxyesters, substituted (S)-2-amino-2-((S)-3-hydroxy-2-oxoindolin-3-yl)acetate, N-(9R)-cinchonan-9-yl-N′-methyl-thiourea, Cinchonine DerivativeAddition Michael Addition, hydantoins, tert-butyl acrylate, chiral hydantoins, (8α,9R)-1-([1,1′-biphenyl]-3-ylmethyl)-9-hydroxy-cinchonanium bromide, Cinchonine DerivativeMichael, Michael Addition Michael Addition, nitroalkenes, α-lithiated phosphonates, 1,2-disubstituted diethyl 3-nitropropylphosphonate, Cinchonine BaseMichael, Michael Addition Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich Spirocyclization, substituted 2-(2-oxoindolin-3-ylidene)malononitrile, 7-substituted 2-hydroxynaphthalene-1,4-dione, spirooxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-10,11-dihydro-6′-methoxy cinchonan-9-yl]-thiourea, Dihydroquinidine DerivativeMichael, Michael Addition, Spirocyclization Trifluoromethoxylation, trifluoromethyl benzoate, 1-(4-vinylphenyl)-1H-1,2,4-triazole, 1,3-dibromo-5,5-dimethylhydantoin, 1-(4-(2-bromo-1-(trifluoromethoxy)ethyl)phenyl)-1H-1,2,4-triazole, silver fluoride, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFurther reactions, Trifluoromethoxylation Resolution, racemic sulfoxides, thioethers, hydrogenperoxide, sulfoxides, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeKinetic resolution, Resolution Atropisomer Synthesis, substituted 1-(3-phenylprop-2-yn-1-yl)urea, N-bromsuccinimid, substituted 1-(2,3-dibromo-3-phenylallyl)urea, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeAtropisomer synthesis, Bromination« Older EntriesNext Entries »
Trifluoromethylation, alkynyl ketones, trimethylsilyl trifluoromethane, trifluoromethylated alkynyl alcohols, (9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[9-hydroxy-cinchonanium bromide (1:2), Cinchonine DerivativeFluorination, Fluoromethylation, Trifluoromethylation
Aldol reaction, substituted 3-(2-aminoethyl)indolin-2-one, formaldehyde, substituted (S)-3-(2-aminoethyl)-3-(hydroxymethyl)indolin-2-one, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine DerivativeAldol, Aldol
Addition, isatins, α‐amido malonic acid half oxyesters, substituted (S)-2-amino-2-((S)-3-hydroxy-2-oxoindolin-3-yl)acetate, N-(9R)-cinchonan-9-yl-N′-methyl-thiourea, Cinchonine DerivativeAddition
Michael Addition, hydantoins, tert-butyl acrylate, chiral hydantoins, (8α,9R)-1-([1,1′-biphenyl]-3-ylmethyl)-9-hydroxy-cinchonanium bromide, Cinchonine DerivativeMichael, Michael Addition
Michael Addition, nitroalkenes, α-lithiated phosphonates, 1,2-disubstituted diethyl 3-nitropropylphosphonate, Cinchonine BaseMichael, Michael Addition
Mannich reaction, 4-benzyl-2-phenyloxazol-5(4H)-one, ethyl 2-((4-methylphenyl)sulfonamido)acrylate, α,β-diamino diacid derivatives, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeMannich, Mannich
Spirocyclization, substituted 2-(2-oxoindolin-3-ylidene)malononitrile, 7-substituted 2-hydroxynaphthalene-1,4-dione, spirooxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(9R)-10,11-dihydro-6′-methoxy cinchonan-9-yl]-thiourea, Dihydroquinidine DerivativeMichael, Michael Addition, Spirocyclization
Trifluoromethoxylation, trifluoromethyl benzoate, 1-(4-vinylphenyl)-1H-1,2,4-triazole, 1,3-dibromo-5,5-dimethylhydantoin, 1-(4-(2-bromo-1-(trifluoromethoxy)ethyl)phenyl)-1H-1,2,4-triazole, silver fluoride, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFurther reactions, Trifluoromethoxylation
Resolution, racemic sulfoxides, thioethers, hydrogenperoxide, sulfoxides, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeKinetic resolution, Resolution
Atropisomer Synthesis, substituted 1-(3-phenylprop-2-yn-1-yl)urea, N-bromsuccinimid, substituted 1-(2,3-dibromo-3-phenylallyl)urea, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeAtropisomer synthesis, Bromination
