Aminohydroxylation, (E)-1-(4-methoxyphenyl)-4-methylpent-1-en-3-one, N-bromoacetamide, N-((1S,2R)-2-hydroxy-1-(4-methoxyphenyl)-4-methyl-3-oxopentyl)acetamide, silica gel-supported (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan, Dihydroquinine DerivativeAminohydroxylation Flow Chemistry, α,β-unsaturated ketones, carbon with two electron-withdrawing groups, β-substituted ketones, Immobilized (8α,9S)-6′-methoxy-3-(1H-1,2,3-triazol-4-yl)-10,11-dinorcinchonan-9-amine, Quinine DerivativeFlow Chemistry, Michael, Michael Addition Strecker reaction, isatin N‐protected ketimines, trimethylsilanecarbonitrile, N-protected (1R)-1-amino-3-methyl-2-oxo-2,3-dihydro-1H-indene-1-carbonitrile, Immobilized N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker Vinylogous Aldol reaction, pyrazole-4,5-diones, allyl ketones, substituted (R,E)-4-hydroxy-4-(4-oxopent-2-en-1-yl)-2,4-dihydro-3H-pyrazol-3-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)-benzamide, Quinine DerivativeAldol, Vinylogous Aldol Alkylation, 3‐substituted oxindoles, brominated hydrocarbons, 3,3‐disubstituted oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAlkylation, Alkylation, alpha-Alkylation Michael Addition, α,β-unsaturated ketones, substituted 2-cyclohexylidenemalononitrile, substituted 2-(2-(3-oxobutyl)cyclohexylidene)malononitrile, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael, Michael Addition Atropisomer Synthesis, arylalkynes, n-bromosuccinimide, acetyl chloride, Z-vicinal dihaloalkene atropisomers, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-4-(trifluoromethyl)benzamide, Quinine DerivativeAtropisomer synthesis Aza-Mannich Addition, oxazolones, N‐protected α‐amido sulfones, substituted 4-(aminomethyl)oxazol-5(4H)-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[(1R)-1-phenylethyl]-thiourea, Quinine DerivativeAza-Mannich, Mannich Michael Addition, substituted 3-amino-1H-pyrrole-2,5-dione, 2,6-di-tert-butyl-4-(2-hydroxybenzylidene)cyclohexa-2,5-dien-1-one, substituted (S)-3-amino-4-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)-1H-pyrrole-2,5-dione, copper catalyst, 1-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)-3-(6-((S)-4-phenyl-4,5-dihydrooxazol-2-yl)pyridin-2-yl)thiourea, Quinine DerivativeMichael, Michael Addition Dynamic Kinetic Resolution, azlactones, hydrazines, amino acid hydrazides, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]thiourea, Quinine DerivativeDynamic Kinetic Resolution, Further reactions, Resolution, Ring opening« Older EntriesNext Entries »
Aminohydroxylation, (E)-1-(4-methoxyphenyl)-4-methylpent-1-en-3-one, N-bromoacetamide, N-((1S,2R)-2-hydroxy-1-(4-methoxyphenyl)-4-methyl-3-oxopentyl)acetamide, silica gel-supported (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan, Dihydroquinine DerivativeAminohydroxylation
Flow Chemistry, α,β-unsaturated ketones, carbon with two electron-withdrawing groups, β-substituted ketones, Immobilized (8α,9S)-6′-methoxy-3-(1H-1,2,3-triazol-4-yl)-10,11-dinorcinchonan-9-amine, Quinine DerivativeFlow Chemistry, Michael, Michael Addition
Strecker reaction, isatin N‐protected ketimines, trimethylsilanecarbonitrile, N-protected (1R)-1-amino-3-methyl-2-oxo-2,3-dihydro-1H-indene-1-carbonitrile, Immobilized N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker
Vinylogous Aldol reaction, pyrazole-4,5-diones, allyl ketones, substituted (R,E)-4-hydroxy-4-(4-oxopent-2-en-1-yl)-2,4-dihydro-3H-pyrazol-3-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)-benzamide, Quinine DerivativeAldol, Vinylogous Aldol
Alkylation, 3‐substituted oxindoles, brominated hydrocarbons, 3,3‐disubstituted oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeAlkylation, Alkylation, alpha-Alkylation
Michael Addition, α,β-unsaturated ketones, substituted 2-cyclohexylidenemalononitrile, substituted 2-(2-(3-oxobutyl)cyclohexylidene)malononitrile, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael, Michael Addition
Atropisomer Synthesis, arylalkynes, n-bromosuccinimide, acetyl chloride, Z-vicinal dihaloalkene atropisomers, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-4-(trifluoromethyl)benzamide, Quinine DerivativeAtropisomer synthesis
Aza-Mannich Addition, oxazolones, N‐protected α‐amido sulfones, substituted 4-(aminomethyl)oxazol-5(4H)-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[(1R)-1-phenylethyl]-thiourea, Quinine DerivativeAza-Mannich, Mannich
Michael Addition, substituted 3-amino-1H-pyrrole-2,5-dione, 2,6-di-tert-butyl-4-(2-hydroxybenzylidene)cyclohexa-2,5-dien-1-one, substituted (S)-3-amino-4-((3,5-di-tert-butyl-4-hydroxyphenyl)(2-hydroxyphenyl)methyl)-1H-pyrrole-2,5-dione, copper catalyst, 1-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)-3-(6-((S)-4-phenyl-4,5-dihydrooxazol-2-yl)pyridin-2-yl)thiourea, Quinine DerivativeMichael, Michael Addition
Dynamic Kinetic Resolution, azlactones, hydrazines, amino acid hydrazides, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]thiourea, Quinine DerivativeDynamic Kinetic Resolution, Further reactions, Resolution, Ring opening
