Michael Addition, cyclohexenone, thiomalonates, S,S-dibenzyl (S)-2-(3-oxocyclohexyl)propanebis(thioate), 2-fluorobenzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael, Michael Addition Michael Addition, 3-benzyl-3-hydroxy-1-(4-nitrophenyl)-4-phenylbutan-2-one, (E)-(2-nitrovinyl)benzene, (4R,5S)-2-benzyl-2-hydroxy-6-nitro-4-(4-nitrophenyl)-1,5-diphenylhexan-3-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Mannich reaction, isatin N-Boc ketimines, α-substituted monothiomalonates, 3,3-disubstituted oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich Spirocyclization, 4-isothiocyanato-2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one, oxindoles, spirooxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeSpirocyclization Atropisomer Synthesis, 2′-((2-hydroxynaphthalen-1-yl)ethynyl)-[1,1′-biphenyl]-3,5-diol, chiral biaryltriols, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAtropisomer synthesis Kinetic Resolution, dibenzo[b,f][1,5]diazocine-6,12(5H,11H)-dione, tert-butyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, planar-chiral dianthranilides, Quinine BaseAlkylation, Alkylation, Dynamic Kinetic Resolution, Kinetic resolution, Resolution Desymmetrization, meso‐cyclic anhydrides, methanol, (1R,2S,3R,4S)-3-(methoxycarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, Quinine BaseDesymmetrization Atropisomer Synthesis, biaryl aldehydes, 2-amino-2,2-diphenylacetic acid, atropisomers, Quinine BaseAmination, Asymmetric Transamination, Atropisomer synthesis, Dynamic Kinetic Resolution, Resolution Oxa-Michael Addition, (E)-7-hydroxy-5-methoxy-8-(2-methylbut-2-enoyl)-4-propyl-2H-chromen-2-one, (8R,9S)-5-methoxy-8,9-dimethyl-4-propyl-8,9-dihydro-2H,10H-pyrano[2,3-f]chromene-2,10-dione, Quinine BaseCyclization, Cyclization, Further Cyclizations, intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition Michael Addition, cyclic N-sulfonylimines, nitroalkenes, 3-((1R,2S)-3-nitro-1,2-diphenylpropyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition« Older EntriesNext Entries »
Michael Addition, cyclohexenone, thiomalonates, S,S-dibenzyl (S)-2-(3-oxocyclohexyl)propanebis(thioate), 2-fluorobenzoic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeMichael, Michael Addition
Michael Addition, 3-benzyl-3-hydroxy-1-(4-nitrophenyl)-4-phenylbutan-2-one, (E)-(2-nitrovinyl)benzene, (4R,5S)-2-benzyl-2-hydroxy-6-nitro-4-(4-nitrophenyl)-1,5-diphenylhexan-3-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Mannich reaction, isatin N-Boc ketimines, α-substituted monothiomalonates, 3,3-disubstituted oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich
Spirocyclization, 4-isothiocyanato-2,5-diphenyl-2,4-dihydro-3H-pyrazol-3-one, oxindoles, spirooxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeSpirocyclization
Atropisomer Synthesis, 2′-((2-hydroxynaphthalen-1-yl)ethynyl)-[1,1′-biphenyl]-3,5-diol, chiral biaryltriols, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAtropisomer synthesis
Kinetic Resolution, dibenzo[b,f][1,5]diazocine-6,12(5H,11H)-dione, tert-butyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate, planar-chiral dianthranilides, Quinine BaseAlkylation, Alkylation, Dynamic Kinetic Resolution, Kinetic resolution, Resolution
Desymmetrization, meso‐cyclic anhydrides, methanol, (1R,2S,3R,4S)-3-(methoxycarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, Quinine BaseDesymmetrization
Atropisomer Synthesis, biaryl aldehydes, 2-amino-2,2-diphenylacetic acid, atropisomers, Quinine BaseAmination, Asymmetric Transamination, Atropisomer synthesis, Dynamic Kinetic Resolution, Resolution
Oxa-Michael Addition, (E)-7-hydroxy-5-methoxy-8-(2-methylbut-2-enoyl)-4-propyl-2H-chromen-2-one, (8R,9S)-5-methoxy-8,9-dimethyl-4-propyl-8,9-dihydro-2H,10H-pyrano[2,3-f]chromene-2,10-dione, Quinine BaseCyclization, Cyclization, Further Cyclizations, intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition
Michael Addition, cyclic N-sulfonylimines, nitroalkenes, 3-((1R,2S)-3-nitro-1,2-diphenylpropyl)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeMichael, Michael Addition
