Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-L-phenylalaninate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation Spirocyclization, 3‐hydroxychromenones, isatylidenemalononitriles, (S)-2-amino-5′-bromo-1′-methyl-2′,10-dioxo-5,10-dihydrospiro[benzo[g]chromene-4,3′-indoline]-3-carbonitrile, 3-(((3S,5S,7S)-adamantan-1-yl)amino)-4-(((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Quinidine DerivativeMichael, Michael Addition, Spirocyclization Decarboxylative Mannich, N-cyano imines, malonic acid half thioesters, substituted 3-cyanamidopropanethioate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMannich, Mannich cascade reaction, α,β-unsaturated ketones, trifluoro-3-oxobutanoates, trifluoromethyl substituted cyclohexanones, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAldol, Aldol, Cascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition Sulfenylation, deconjugated butyrolactams, substituted 1-mercaptopyrrolidine-2,5-dione, substituted 1-selenopyrrolidine-2,5-dione, chiral butyrolactams, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation Addition, kojic acid derivatives, β-nitroolefins, 6-(((tert-butyldimethylsilyl)oxy)methyl)-3-hydroxy-2-(2-nitro-1-phenylethyl)-4H-pyran-4-one, (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(3-((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)tetrahydro-2H-pyran-3,4,5-triyl triacetate, Quinidine DerivativeAddition Spirocyclization, oxindoles, (E)-4-mercaptobut-2-enoates, spirocyclic oxindoles, (1S,2R,4S,5R)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((10-phenylanthracen-9-yl)methyl)-5-vinylquinuclidin-1-ium chloride, Quinidine DerivativeMichael Addition, Spirocyclization, Sulfa-Michael, Sulfa-Michael Addition Amination, tertiary amides, heptafluorobutyl sulfamate, heptafluorobutyl (R)-(1-(2-fluorophenyl)-4-(methyl(phenyl)amino)-4-oxobutyl)sulfamate, rhodium complexes, (9S)-11,12-dihydro-9-hydroxy-6′-methoxy-1-([1,1′:3′,1′′-terphenyl]-5′-ylmethyl)-cinchonanium, Dihydroquinidine DerivativeAmination, gamma-Amination Atropisomer Synthesis, 2-Arylindoles, arylmethylbromides, atropisomeric indoles, (9S)-1-[(2-methylphenyl)methyl]-9-(phenylmethoxy)-cinchonanium bromide, Cinchonine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution Desymmetrization, keto sulfonium salts, (R,E)-5-(methylthio)-1,5-diphenylpent-1-en-3-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeDesymmetrization« Older EntriesNext Entries »
Decarboxylative Protonation, 2-acetamido-2-benzyl-3-ethoxy-3-oxopropanoic acid, ethyl acetyl-L-phenylalaninate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeDecarboxylative Protonation, Protonation
Spirocyclization, 3‐hydroxychromenones, isatylidenemalononitriles, (S)-2-amino-5′-bromo-1′-methyl-2′,10-dioxo-5,10-dihydrospiro[benzo[g]chromene-4,3′-indoline]-3-carbonitrile, 3-(((3S,5S,7S)-adamantan-1-yl)amino)-4-(((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Quinidine DerivativeMichael, Michael Addition, Spirocyclization
Decarboxylative Mannich, N-cyano imines, malonic acid half thioesters, substituted 3-cyanamidopropanethioate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine DerivativeMannich, Mannich
cascade reaction, α,β-unsaturated ketones, trifluoro-3-oxobutanoates, trifluoromethyl substituted cyclohexanones, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAldol, Aldol, Cascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael, Michael Addition
Sulfenylation, deconjugated butyrolactams, substituted 1-mercaptopyrrolidine-2,5-dione, substituted 1-selenopyrrolidine-2,5-dione, chiral butyrolactams, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine DerivativeSulfenylation
Addition, kojic acid derivatives, β-nitroolefins, 6-(((tert-butyldimethylsilyl)oxy)methyl)-3-hydroxy-2-(2-nitro-1-phenylethyl)-4H-pyran-4-one, (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(3-((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)tetrahydro-2H-pyran-3,4,5-triyl triacetate, Quinidine DerivativeAddition
Spirocyclization, oxindoles, (E)-4-mercaptobut-2-enoates, spirocyclic oxindoles, (1S,2R,4S,5R)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((10-phenylanthracen-9-yl)methyl)-5-vinylquinuclidin-1-ium chloride, Quinidine DerivativeMichael Addition, Spirocyclization, Sulfa-Michael, Sulfa-Michael Addition
Amination, tertiary amides, heptafluorobutyl sulfamate, heptafluorobutyl (R)-(1-(2-fluorophenyl)-4-(methyl(phenyl)amino)-4-oxobutyl)sulfamate, rhodium complexes, (9S)-11,12-dihydro-9-hydroxy-6′-methoxy-1-([1,1′:3′,1′′-terphenyl]-5′-ylmethyl)-cinchonanium, Dihydroquinidine DerivativeAmination, gamma-Amination
Atropisomer Synthesis, 2-Arylindoles, arylmethylbromides, atropisomeric indoles, (9S)-1-[(2-methylphenyl)methyl]-9-(phenylmethoxy)-cinchonanium bromide, Cinchonine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution
Desymmetrization, keto sulfonium salts, (R,E)-5-(methylthio)-1,5-diphenylpent-1-en-3-one, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(9R)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonine DerivativeDesymmetrization
