Michael Addition, chalcones, malononitrile, 2-(3-aryl-1-substituted-3-oxopropyl)malononitrile, triisopropoxyaluminum, Quinine BaseMichael, Michael Addition Spirocyclization/Domino Michael Addition, 3-isothiocyanato oxindoles, unsaturated pyrazolones, spirocyclic oxindoles, Quinine BaseCascade reaction, Spirocyclization Spirocyclization/domino Michael/Michael Addition, 2-arylidene-1,3-indandiones, curcumins, multicyclic spiro-1,3-indandiones, Quinine BaseCascade reaction, Spirocyclization Aza-Henry (Nitro Mannich), fluoromethylated imines, nitromethane, fluoromethylated beta-nitroamines, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Henry (Nitroaldol), 1,1,1-trifluoro-3-phenylpropan-2-one, nitromethane, (S)-1,1,1-trifluoro-2-nitro-3-phenylpropan-2-ol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]oxy]-10,11-dihydro-6′-methoxycinchonan-5′-yl]-urea, Dihydroquinine DerivativeAldol, Henry, Henry, Nitroaldol Michael Addition, ethyl 2-fluoro-3-(4-nitrophenyl)-3-oxopropanoate, 1-benzyl-1H-pyrrole-2,5-dione, ethyl (R)-2-((R)-1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-fluoro-3-(4-nitrophenyl)-3-oxopropanoate, (3β,8α,9R)-3-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecyl)-6′-methoxy-10,11-Dinorcinchonan-9-ol, Dihydroquinine DerivativeMichael, Michael Addition Michael Addition, 2-hydroxynaphthalene-1,4-dione, nitroalkenes, 2-(1-substituted-2-nitroethyl)-3-hydroxynaphthalene-1,4-dione, N-[(8α,9R)-10,11-Dihydro-6′-methoxycinchonan-9-yl]-N′- (2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-thiourea, Dihydroquinine DerivativeMichael, Michael Addition Michael Addition, methyl 2-oxocyclopentane-1-carboxylate, (E)-(2-nitrovinyl)benzene, methyl (R)-1-((S)-2-nitro-1-phenylethyl)-2-oxocyclopentane-1-carboxylate, (8α,9R)-10,11-Dihydro-6′-methoxy-5′-nitrocinchonan-9-ol, Dihydroquinine DerivativeMichael, Michael Addition Spirocyclization/Cyclopropanation/Michael Addition/Alkylation, 3-(substituted methylene) oxindoles, 1-bromo-1-nitroethane, spiro nitrocyclopropyl oxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Spirocyclization Spirocyclization/Aza-Michael/Michael cascade, 3‐ylideneoxindoles, tosylaminomethyl enones or enoates, spiro-[pyrrolidine-3,3′-oxindole]s, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization« Older EntriesNext Entries »
Michael Addition, chalcones, malononitrile, 2-(3-aryl-1-substituted-3-oxopropyl)malononitrile, triisopropoxyaluminum, Quinine BaseMichael, Michael Addition
Spirocyclization/Domino Michael Addition, 3-isothiocyanato oxindoles, unsaturated pyrazolones, spirocyclic oxindoles, Quinine BaseCascade reaction, Spirocyclization
Spirocyclization/domino Michael/Michael Addition, 2-arylidene-1,3-indandiones, curcumins, multicyclic spiro-1,3-indandiones, Quinine BaseCascade reaction, Spirocyclization
Aza-Henry (Nitro Mannich), fluoromethylated imines, nitromethane, fluoromethylated beta-nitroamines, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Henry (Nitroaldol), 1,1,1-trifluoro-3-phenylpropan-2-one, nitromethane, (S)-1,1,1-trifluoro-2-nitro-3-phenylpropan-2-ol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]oxy]-10,11-dihydro-6′-methoxycinchonan-5′-yl]-urea, Dihydroquinine DerivativeAldol, Henry, Henry, Nitroaldol
Michael Addition, ethyl 2-fluoro-3-(4-nitrophenyl)-3-oxopropanoate, 1-benzyl-1H-pyrrole-2,5-dione, ethyl (R)-2-((R)-1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-fluoro-3-(4-nitrophenyl)-3-oxopropanoate, (3β,8α,9R)-3-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecyl)-6′-methoxy-10,11-Dinorcinchonan-9-ol, Dihydroquinine DerivativeMichael, Michael Addition
Michael Addition, 2-hydroxynaphthalene-1,4-dione, nitroalkenes, 2-(1-substituted-2-nitroethyl)-3-hydroxynaphthalene-1,4-dione, N-[(8α,9R)-10,11-Dihydro-6′-methoxycinchonan-9-yl]-N′- (2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-thiourea, Dihydroquinine DerivativeMichael, Michael Addition
Michael Addition, methyl 2-oxocyclopentane-1-carboxylate, (E)-(2-nitrovinyl)benzene, methyl (R)-1-((S)-2-nitro-1-phenylethyl)-2-oxocyclopentane-1-carboxylate, (8α,9R)-10,11-Dihydro-6′-methoxy-5′-nitrocinchonan-9-ol, Dihydroquinine DerivativeMichael, Michael Addition
Spirocyclization/Cyclopropanation/Michael Addition/Alkylation, 3-(substituted methylene) oxindoles, 1-bromo-1-nitroethane, spiro nitrocyclopropyl oxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Spirocyclization
Spirocyclization/Aza-Michael/Michael cascade, 3‐ylideneoxindoles, tosylaminomethyl enones or enoates, spiro-[pyrrolidine-3,3′-oxindole]s, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization
