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alpha-Amination, arylketones, diethyl (E)-diazene-1,2-dicarboxylate, alpha-amino aryl ketones, (9R)-Cinchonan-9-amine, Cinchonine Derivative

alpha-Amination, Amination, Further reactions

Amination of alpha-branched aldehydes, 2-phenylpropanal, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl (S)-1-(1-oxo-2-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate, (-)-Camphorsulfonic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Amination, Further reactions

Strecker reaction, 6-chloro-1-(4-methoxybenzyl)-4-(trifluoromethyl)quinazolin-2(1H)-one, trimethylsilanecarbonitrile, (R)-6-chloro-1-(4-methoxybenzyl)-2-oxo-4-(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-4-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Strecker

[2+2] Cycloaddition, N-sulfonylimines, allenoates, 2,4-disubstituted azetidines, 1,1-Dimethylethyl N-[2-oxo-2-[[(9S)-9-(phenylmethoxy)cinchonan-6′-yl]amino]ethyl]carbamate, 6´-Aminocinchonine Derivative

[2+2]-Cycloaddition, Cycloaddition

Sulfa-Michael Addition, (E)-3-(3-substituted-acryloyl)oxazolidin-2-one, thiols, (S)-3-(3-substituted-3-mercaptopropanoyl)oxazolidin-2-one, 4-(Dimethylamino)-N-[(9S)-9-(phenylmethoxy)cinchonan-6′-yl]benzenesulfonamide, 6´-Aminocinchonine Derivative

Michael Addition, Sulfa-Michael

Henry reaction (Nitroaldol), benzaldehyde, nitromethane, (S)-2-nitro-1-phenylethan-1-ol, N-[(9S)-9-Methoxycinchonan-6′-yl]-N′-phenylthiourea, 6´-Aminocinchonine Derivative

Aldol, Henry, Henry, Nitroaldol

Cyclopropanation, tert-butyl 2-bromoacetate, 1-phenylprop-2-en-1-one, tert-butyl (1S,2S)-2-benzoylcyclopropane-1-carboxylate, (8α,9R)-6′,9-Dimethoxycinchonan, Quinine Derivative

Cyclopropanation

Aza-Henry (Nitro-Mannich), N-(benzo[d]thiazol-2-yl)-1-phenylmethanimine, nitromethane, N-(2-nitro-1-phenylethyl)benzo[d]thiazol-2-amine, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

Aza-Henry, Henry, Mannich, Nitro-Mannich

Nitro-Mannich (Aza-Henry), alpha-amido sulfones, nitroalkanes, beta-nitroamines, (8α,9R)-1-(1H-benzotriazol-1-ylmethyl)-9-hydroxy-6′-methoxy-Cinchonanium chloride, Quinine Derivative

Aza-Henry, Henry, Mannich, Nitro-Mannich

Henry reaction (Nitroaldol), aldehydes, nitromethane, beta-nitroalcohols, 2,4-Bis(1,1-dimethylethyl)-6-[(E)-[[(8α,9S)-6′-methoxycinchonan-9-yl]imino]methyl]-Phenol, Quinine Derivative

Aldol, Henry, Henry, Nitroaldol

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