Alkylation, tert-butyl 2-((diphenylmethylene)amino)acetate, cyclopent-1-ene-1-carbaldehyde, tert-butyl (S)-2-((diphenylmethylene)amino)-2-((1S,2R)-2-formylcyclopentyl)acetate and tert-butyl (S)-2-((diphenylmethylene)amino)-2-((1S,2S)-2-formylcyclopentyl)acetate, (8α,9R)-1-(9-anthracenylmethyl)-9- (2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation Mannich reaction, N-Boc-protected imines, glycine Schiff bases, alpha,beta-diamino acid derivatives, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMannich, Mannich Desymmetrization, 4-((tert-butyldiphenylsilyl)oxy)dihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-((tert-butyldiphenylsilyl)oxy)-5-methoxy-5-oxopentanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization Desymmetrization, 4-propyldihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-(2-methoxy-2-oxoethyl)hexanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization Intermolecular Desymmetrization, 1,3-diketones, beta,gamma unsaturated alpha ketoester, 1,4-dihydropyridines, 3-[(2-Fluorophenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeDesymmetrization Alkylative Desymmetrization, 2,2-disubstituted cyclopentene-1,3-diones, nitroalkanes, 4-alkyl-2,2-disubstitutedcyclopentene-1,3-diones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeDesymmetrization Desymmetrization, N-benzhydryl-2,2,2-trifluoroacetamide, Bis(pinacolato)diborane, hydrogen peroxide, (S)-2,2,2-trifluoro-N-((3-hydroxyphenyl)(phenyl)methyl)acetamide, Bis(1,5-cyclooctadiene)dimethoxydiiridium, (8α,9R)-10,11-dihydro-9-hydroxy-6′-methoxy-1-[[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-Cinchonanium 5′-methyl[2,2′-bipyridine]-5-methanesulfonate, Dihydroquinine DerivativeDesymmetrization Desymmetrization, substituted cyclohexa-2,5-dien-1-ones, isocyano(arylsulfonyl)methane, substituted 2,7-dihydro-4H-isoindol-4-one, Silver iodide, N-(8α,9S)-Cinchonan-9-yl-2-(diphenylphosphino)benzamide, Cinchonidine DerivativeDesymmetrization Aldol reaction, 3-((4-fluorophenyl)thio)-3-oxopropanoic acid, 2,2,2-trifluoro-1-phenylethan-1-one, S-(4-fluorophenyl) (S)-4,4,4-trifluoro-3-hydroxy-3-phenylbutanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeAldol, Aldol Hydrophosphonylation, isatins derived ketimines, diphenyl phosphite, 3-substituted 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeHydrophosphonylation« Older EntriesNext Entries »
Alkylation, tert-butyl 2-((diphenylmethylene)amino)acetate, cyclopent-1-ene-1-carbaldehyde, tert-butyl (S)-2-((diphenylmethylene)amino)-2-((1S,2R)-2-formylcyclopentyl)acetate and tert-butyl (S)-2-((diphenylmethylene)amino)-2-((1S,2S)-2-formylcyclopentyl)acetate, (8α,9R)-1-(9-anthracenylmethyl)-9- (2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation
Mannich reaction, N-Boc-protected imines, glycine Schiff bases, alpha,beta-diamino acid derivatives, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMannich, Mannich
Desymmetrization, 4-((tert-butyldiphenylsilyl)oxy)dihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-((tert-butyldiphenylsilyl)oxy)-5-methoxy-5-oxopentanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]- 3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization
Desymmetrization, 4-propyldihydro-2H-pyran-2,6(3H)-dione, methanol, (R)-3-(2-methoxy-2-oxoethyl)hexanoic acid, N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide, Quinine DerivativeDesymmetrization
Intermolecular Desymmetrization, 1,3-diketones, beta,gamma unsaturated alpha ketoester, 1,4-dihydropyridines, 3-[(2-Fluorophenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeDesymmetrization
Alkylative Desymmetrization, 2,2-disubstituted cyclopentene-1,3-diones, nitroalkanes, 4-alkyl-2,2-disubstitutedcyclopentene-1,3-diones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeDesymmetrization
Desymmetrization, N-benzhydryl-2,2,2-trifluoroacetamide, Bis(pinacolato)diborane, hydrogen peroxide, (S)-2,2,2-trifluoro-N-((3-hydroxyphenyl)(phenyl)methyl)acetamide, Bis(1,5-cyclooctadiene)dimethoxydiiridium, (8α,9R)-10,11-dihydro-9-hydroxy-6′-methoxy-1-[[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-Cinchonanium 5′-methyl[2,2′-bipyridine]-5-methanesulfonate, Dihydroquinine DerivativeDesymmetrization
Desymmetrization, substituted cyclohexa-2,5-dien-1-ones, isocyano(arylsulfonyl)methane, substituted 2,7-dihydro-4H-isoindol-4-one, Silver iodide, N-(8α,9S)-Cinchonan-9-yl-2-(diphenylphosphino)benzamide, Cinchonidine DerivativeDesymmetrization
Aldol reaction, 3-((4-fluorophenyl)thio)-3-oxopropanoic acid, 2,2,2-trifluoro-1-phenylethan-1-one, S-(4-fluorophenyl) (S)-4,4,4-trifluoro-3-hydroxy-3-phenylbutanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeAldol, Aldol
Hydrophosphonylation, isatins derived ketimines, diphenyl phosphite, 3-substituted 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeHydrophosphonylation
