Buchler GmbH
  • Products
    • Active Pharmaceutical Ingredients
    • Asymmetric Synthesis
      • Chiral Building Blocks
      • Chiral Phase Transfer Catalysts (PTCs)
      • Chiral Screening Kit
      • Enantioselective Organocatalysts
      • Racemic Resolution
    • Food Ingredients
    • Product Overview
  • Chiral Catalyst Search (NEW)
  • Contact
  • About
    • Certificates
    • Company Policy
    • Former Buchler Company Managers
    • Galleries
      • Gallery current production and storage
      • Gallery Laboratory
      • Gallery Historical Production
    • History of Buchler
  • Career
Select Page

Aza-Michael Addition, diacrylbenzols, N‐benzylhydroxylamine, 1,2‐benzoxazines, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinidine Derivative

Aza-Michael, Cascade reaction, Cyclization, Cyclization, Further Cyclizations, Michael Addition, Oxa-Michael Addition

Phosphination, butyl 2-cyanopentanoate, chlorodiphenylphosphane, butyl (R)-2-cyano-2-(diphenylphosphaneyl)pentanoate, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)] bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine Derivative

Further reactions, Phosphination

Cyclization, O‐allyl carbamates, N-bromosuccinimide, (4S,5S)-5-bromo-4-phenyl-3-tosyl-1,3-oxazinan-2-one, O-((S)-((1S,2R,4S,5R)-5-ethylquinuclidin-2-yl)(quinolin-4-yl)methyl) phenylcarbamothioate, Dihydrocinchonine Derivative

Bromination, Cyclization, Cyclization, Further Cyclizations

Desymmetrization, (1R,2S)-cyclohexane-1,2-diol, oxygen, (S)-2-hydroxycyclohexan-1-one, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine Derivative

Desymmetrization

Epimerization, substituted (1R,2S)-cyclohexane-1,2-diol, substituted (1S,2S)-cyclohexane-1,2-diol, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine Derivative

Desymmetrization, Isomerization

Epimerization, (1R,2S)-cycloheptane-1,2-diol, (1S,2S)-cycloheptane-1,2-diol, 4CzIPN, N-[(9R)-10,11-dihydrocinchonan-9-yl]-O-tert-butyl carbamate, Dihydrocinchonine Derivative

Desymmetrization, Isomerization

Trifluoromethylation, (E)-1-(3-bromophenyl)-3-phenylbut-3-en-1-one oxime, (S)-3-(3-bromophenyl)-5-phenyl-5-(2,2,2-trifluoroethyl)-4,5-dihydroisoxazole, copper acetate, N-[(9R)-10,11-dihydrocinchonan-9-yl]-2,3,4,5,6-pentamethyl-benzenesulfonamide, Dihydrocinchonine Derivative

Cyclization, Fluorination, Fluoromethylation, Isoxazoline cyclization, Trifluoromethylation

Oxa-Michael Addition, methyl (E)-4-(2-hydroxyphenyl)but-2-enoate, methyl 2-(2,3-dihydrobenzofuran-2-yl)acetate, Dihydrocinchonine Base

Cyclization, Further Cyclizations, Intramolecular cyclization, intramolecular Oxa-Michael Addition, Michael Addition, Oxa-Michael Addition

Sulfa-Michael Addition, α,β-unsaturated N-acylated oxazolidin-2-ones, alkyl thiols, γ-thio ketones, N-[(9S)-9-(9-anthracenylmethoxy)cinchonan-6′-yl]-N′-[3,5-bis(trifluoromethyl)phenyl]-thiourea, 6´-Aminocinchonine Derivative

Michael Addition, Sulfa-Michael, Sulfa-Michael Addition

Michael Addition, thioester malonates, (E)-1-((4-methoxybenzyl)oxy)-2-(2-nitrovinyl)benzene, 4-methoxybenzyl (2S,3S)-3-(2-((4-methoxybenzyl)oxy)phenyl)-2-(((4-methoxyphenyl)thio)carbonyl)-2-methyl-4-nitrobutanoate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-urea, Cinchonine Derivative

Michael, Michael Addition

« Older Entries
Next Entries »

Glossary

Impressum / Legal Notice

Code of Conduct

Hinweisgebersystem / Whistleblowing System

Allgemeine Geschäfts-bedingungen / General Terms and Conditions

Datenschutzhinweise / Data Protection Information

Contact

My Account
  • Follow
  • Follow

All Rights Reserved by Buchler GmbH