Michael Addition, butanone, (E)-(2-nitrovinyl)benzene, (3R,4S)-3-methyl-5-nitro-4-phenylpentan-2-one, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition Michael Addition, trans-β-nitrostyrene, pentane-2,4-dione, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-(((1S)-((2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)amino)-4-(R)-(((2′-methyl-[1,1′-binaphthalen]-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition Michael Addition, enones, oxindoles, substituted (S)-3-methyl-3-((R)-4-oxopentan-2-yl)indolin-2-one, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition Atropisomer synthesis, 2′-methoxy-3,4-dihydro-[1,1′-binaphthalen]-2(1H)-one, benzyl iodide, (S)-2-(benzyloxy)-2′-methoxy-1,1′-binaphthalene, (9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis Trifluoromethylthiolation, Substituted (3E)-2-oxo-3-(substituted-methylene)cyclopentanecarboxylate, 1-((trifluoromethyl)thio)pyrrolidine-2,5-dione, 5-substituted 2-mercaptobenzaldehyde, spiro-cyclopentanone–thiochromanes, 3-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)amino]-3-cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization, Trifluoro-methylthiolation Desymmetrization, prochiral cyclic anhydrides, methanol, chiral hemiesters, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeDesymmetrization Friedel-crafts, 2-Methoxy-6-[[(4-methylphenyl)sulfonyl]phenylmethyl]phenol, 7-Hydroxyindole, (R)-6-((2-hydroxy-3-methoxyphenyl)(phenyl)methyl)-1H-indol-7-ol, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFriedel-Crafts, Friedel-Crafts reaction Aldol reaction, S-substituted 2-chloro-3-mercapto-3-oxopropanoic acid, aldehydes, (3S)-substituted (2S)-2-chloro-3-hydroxypropanethioesters, N-[[[(9R)-6′-methoxycinchonan-9-yl]amino]carbonyl]-4-methyl-benzenesulfonamide, Quinidine DerivativeAldol, Aldol Sulfur dioxide insertion, 1-alkynylnaphthalen-2-ols, potassium alkyltrifluoroborates, potassium metabisulfite, (S,E)-1-(1-(alkylsulfonyl)-2-vinyl)naphthalen-2-ols, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAtropisomer synthesis, Further reactions, Sulfur dioxide insertion Chiral Peptide synthesis, amino acid methyl esters, racemic N-protected amino acids, peptides, (9S)-1,1′-bis(4,6-dimethoxy-1,3,5-triazin-2-yl)-9-hydroxy-6′-methoxy-cinchonanium tetrafluoroborate, Quinidine DerivativeAcylation, Further reactions, Peptide synthesis« Older EntriesNext Entries »
Michael Addition, butanone, (E)-(2-nitrovinyl)benzene, (3R,4S)-3-methyl-5-nitro-4-phenylpentan-2-one, L-proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeMichael, Michael Addition
Michael Addition, trans-β-nitrostyrene, pentane-2,4-dione, (S)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-(((1S)-((2S,4S,5R)-5-Ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)amino)-4-(R)-(((2′-methyl-[1,1′-binaphthalen]-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione, Dihydroquinine DerivativeMichael, Michael Addition
Michael Addition, enones, oxindoles, substituted (S)-3-methyl-3-((R)-4-oxopentan-2-yl)indolin-2-one, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeMichael, Michael Addition
Atropisomer synthesis, 2′-methoxy-3,4-dihydro-[1,1′-binaphthalen]-2(1H)-one, benzyl iodide, (S)-2-(benzyloxy)-2′-methoxy-1,1′-binaphthalene, (9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis
Trifluoromethylthiolation, Substituted (3E)-2-oxo-3-(substituted-methylene)cyclopentanecarboxylate, 1-((trifluoromethyl)thio)pyrrolidine-2,5-dione, 5-substituted 2-mercaptobenzaldehyde, spiro-cyclopentanone–thiochromanes, 3-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)amino]-3-cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization, Trifluoro-methylthiolation
Desymmetrization, prochiral cyclic anhydrides, methanol, chiral hemiesters, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeDesymmetrization
Friedel-crafts, 2-Methoxy-6-[[(4-methylphenyl)sulfonyl]phenylmethyl]phenol, 7-Hydroxyindole, (R)-6-((2-hydroxy-3-methoxyphenyl)(phenyl)methyl)-1H-indol-7-ol, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFriedel-Crafts, Friedel-Crafts reaction
Aldol reaction, S-substituted 2-chloro-3-mercapto-3-oxopropanoic acid, aldehydes, (3S)-substituted (2S)-2-chloro-3-hydroxypropanethioesters, N-[[[(9R)-6′-methoxycinchonan-9-yl]amino]carbonyl]-4-methyl-benzenesulfonamide, Quinidine DerivativeAldol, Aldol
Sulfur dioxide insertion, 1-alkynylnaphthalen-2-ols, potassium alkyltrifluoroborates, potassium metabisulfite, (S,E)-1-(1-(alkylsulfonyl)-2-vinyl)naphthalen-2-ols, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAtropisomer synthesis, Further reactions, Sulfur dioxide insertion
Chiral Peptide synthesis, amino acid methyl esters, racemic N-protected amino acids, peptides, (9S)-1,1′-bis(4,6-dimethoxy-1,3,5-triazin-2-yl)-9-hydroxy-6′-methoxy-cinchonanium tetrafluoroborate, Quinidine DerivativeAcylation, Further reactions, Peptide synthesis
