Dihydroxylation, 1,1-disubstituted aliphatic alkenes, (R)-2-methyl-3-((4-(3,4,5-trimethoxyphenyl)phthalazin-1-yl)oxy)propane-1,2-diol, dipotassium osmate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis (oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeDihydroxylation Sulfa-Michael Addition, (E)-2-(2-nitrovinyl)pyridine, (4-(tert-butyl)phenyl)methanethiol, (R)-2-(1-((4-(tert-butyl)benzyl)thio)-2-nitroethyl)pyridine, N-[3,5-bis(trifluoromethyl)phenyl]-N-[(8α,9R)-9-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10,11-dihydro-6′-methoxycinchonan-5′-yl]-urea, Dihydroquinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Baeyer-Villiger Oxidation, 3-(naphthalen-1-yl)cyclobutan-1-one, hydrogen peroxide, (S)-4-(naphthalen-1-yl)dihydrofuran-2(3H)-one, flavinium catalyst, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis (oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeBaeyer-Villiger Oxidation, Further reactions, Oxidation Cyanosilylation, diazooxindoles, 2,5-disubstituted furan, trimethylsilyl cyanide, 3-alkenyloxindoles, chloro(triphenylphosphine)gold, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCyanation, Cyanosilylation, Further reactions Strecker Synthesis, dibenzo[b,f][1,4]oxazepines, trimethylsilyl cyanide, substituted (R)-10,11-dihydrodibenzo[b,f][1,4]oxazepine-11-carbonitrile, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeStrecker Mannich reaction, 3-fluorooxindoles, dibenzo[b,f][1,4]oxazepines, tetrasubstituted C–F stereocenters, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-thiourea, Dihydroquinine DerivativeMannich, Mannich Spirocyclization, substituted 1-(2-(3-oxocyclobutyl)phenyl)hept-4-ene-1,6-dione, cyclobutanone fused oxa-spirocycles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization Atropisomer Synthesis, 1-(alkynyl)naphthalen-2-ols, cyclopropanols, DABCO-bis(sulfur dioxide), atropisomeric sulfonyls, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAtropisomer synthesis, Sulfonylation Michael Addition, 2-(4-nitrophenyl)-1-(1H-pyrazol-1-yl)ethan-1-one, (E)-1-(2-nitrovinyl)-2-(trifluoromethyl)benzene, (2R,3S)-4-nitro-2-(4-nitrophenyl)-1-(1H-pyrazol-1-yl)-3-(2-(trifluoromethyl)phenyl)butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeMichael, Michael Addition Cyclization, aminochalcones, azlactones, 3,4-dihydroquinolinones, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCyclization, Cyclization, Further Cyclizations« Older EntriesNext Entries »
Dihydroxylation, 1,1-disubstituted aliphatic alkenes, (R)-2-methyl-3-((4-(3,4,5-trimethoxyphenyl)phthalazin-1-yl)oxy)propane-1,2-diol, dipotassium osmate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis (oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeDihydroxylation
Sulfa-Michael Addition, (E)-2-(2-nitrovinyl)pyridine, (4-(tert-butyl)phenyl)methanethiol, (R)-2-(1-((4-(tert-butyl)benzyl)thio)-2-nitroethyl)pyridine, N-[3,5-bis(trifluoromethyl)phenyl]-N-[(8α,9R)-9-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10,11-dihydro-6′-methoxycinchonan-5′-yl]-urea, Dihydroquinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Baeyer-Villiger Oxidation, 3-(naphthalen-1-yl)cyclobutan-1-one, hydrogen peroxide, (S)-4-(naphthalen-1-yl)dihydrofuran-2(3H)-one, flavinium catalyst, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis (oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeBaeyer-Villiger Oxidation, Further reactions, Oxidation
Cyanosilylation, diazooxindoles, 2,5-disubstituted furan, trimethylsilyl cyanide, 3-alkenyloxindoles, chloro(triphenylphosphine)gold, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCyanation, Cyanosilylation, Further reactions
Strecker Synthesis, dibenzo[b,f][1,4]oxazepines, trimethylsilyl cyanide, substituted (R)-10,11-dihydrodibenzo[b,f][1,4]oxazepine-11-carbonitrile, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeStrecker
Mannich reaction, 3-fluorooxindoles, dibenzo[b,f][1,4]oxazepines, tetrasubstituted C–F stereocenters, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-thiourea, Dihydroquinine DerivativeMannich, Mannich
Spirocyclization, substituted 1-(2-(3-oxocyclobutyl)phenyl)hept-4-ene-1,6-dione, cyclobutanone fused oxa-spirocycles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCascade reaction, Spirocyclization
Atropisomer Synthesis, 1-(alkynyl)naphthalen-2-ols, cyclopropanols, DABCO-bis(sulfur dioxide), atropisomeric sulfonyls, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAtropisomer synthesis, Sulfonylation
Michael Addition, 2-(4-nitrophenyl)-1-(1H-pyrazol-1-yl)ethan-1-one, (E)-1-(2-nitrovinyl)-2-(trifluoromethyl)benzene, (2R,3S)-4-nitro-2-(4-nitrophenyl)-1-(1H-pyrazol-1-yl)-3-(2-(trifluoromethyl)phenyl)butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Urea, Dihydroquinine DerivativeMichael, Michael Addition
Cyclization, aminochalcones, azlactones, 3,4-dihydroquinolinones, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeCyclization, Cyclization, Further Cyclizations
