Henry reaction, ethyl (E)-2-oxopent-3-enoate, nitromethane, ethyl (R,E)-2-hydroxy-2-(nitromethyl)pent-3-enoate, (9S)-cinchonan-6′,9-diol-9-benzoate, Cupreidine DerivativeHenry, Henry Alkylation, 1-(bromomethyl)-3,5-dimethoxybenzene, dimethyl 2-oxo-2,3-dihydro-1H-indene-1,3-dicarboxylate, dimethyl (S)-3-(3,5-dimethoxybenzyl)-2-oxoindoline-1,3-dicarboxylate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]-2′-chloro-10,11-dihydro-6′-methoxy-Cinchonanium bromide, Dihydroquinine DerivativeAlkylation, Alkylation Spirocyclization, alkylidene oxindoles, nitroketones, spiro-cyclopentaneoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Spirocyclization Domino Annulation, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-one, substituted tert-butyl ((2-hydroxyphenyl)(tosyl)methyl)carbamate, substituted tert-butyl ((4bS,10R,10aR)-13-thioxo-10H,11H-4b,10a-(epiminomethanoimino)indeno[1,2-b]chromen-10-yl)carbamate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Cyclization, Cycloaddition Cascade reaction, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-ones, substituted (E)-4-benzylidene-1-phenylpyrrolidine-2,3-diones, substituted (2R,3’R,4’S)-1”,3′-diphenyl-5′-thioxodispiro[indene-2,2′-pyrrolidine-4′,3”-pyrrolidine]-1,4”,5”(3H)-triones, (9R)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(4-nitrophenyl)amino]-4-[(4-nitrophenyl)amino]-3-Cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization Henry reaction, 2-substituted ethyl 2-oxoacetate, nitromethane, 2-substituted ethyl (S)-2-hydroxy-3-nitro-propanoate, (9S)-cinchonan-6′,9-diol-9-benzoate, Cupreidine DerivativeHenry, Henry Michael Addition, 1-oxoindan-2-carbonitrile, 2-chloroacrylonitrile, (S)-2-((R)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, Cupreidine BaseMichael, Michael Addition Kinetic resolution, ethyl (E)-4-cyclopropyl-4-(1,3-dioxoisoindolin-2-yl)but-2-enoate, ethyl (R,E)-4-cyclopropyl-4-(1,3-dioxoisoindolin-2-yl)but-2-enoate, (8α,9R)-9-[[4,6-Bis(4-methoxyphenyl)-1,3,5-triazin-2-yl]oxy]-10,11-dihydro-6′-methoxy-Cinchonan, Dihydroquinine DerivativeKinetic resolution, Resolution Vinylogous Aldol, 5H-2-furanone, aldehydes, hydroxyalkylfuranones, N-[(2S)-2-[[2-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3-phenylpropyl]-1,1,2,2,3,3,4,4,4-nonafluoro-1-Butanesulfonamide, Dihydroquinine DerivativeAldol, Vinylogous Aldol Michael Addition, (E)-1,2,3-trifluoro-5-(2-nitrovinyl)benzene, diethyl malonate, diethyl (R)-2-(2-nitro-1-(3,4,5-trifluorophenyl)ethyl)malonate, Cupreidine BaseMichael, Michael Addition« Older EntriesNext Entries »
Henry reaction, ethyl (E)-2-oxopent-3-enoate, nitromethane, ethyl (R,E)-2-hydroxy-2-(nitromethyl)pent-3-enoate, (9S)-cinchonan-6′,9-diol-9-benzoate, Cupreidine DerivativeHenry, Henry
Alkylation, 1-(bromomethyl)-3,5-dimethoxybenzene, dimethyl 2-oxo-2,3-dihydro-1H-indene-1,3-dicarboxylate, dimethyl (S)-3-(3,5-dimethoxybenzyl)-2-oxoindoline-1,3-dicarboxylate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]amino]-2′-chloro-10,11-dihydro-6′-methoxy-Cinchonanium bromide, Dihydroquinine DerivativeAlkylation, Alkylation
Spirocyclization, alkylidene oxindoles, nitroketones, spiro-cyclopentaneoxindoles, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Spirocyclization
Domino Annulation, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-one, substituted tert-butyl ((2-hydroxyphenyl)(tosyl)methyl)carbamate, substituted tert-butyl ((4bS,10R,10aR)-13-thioxo-10H,11H-4b,10a-(epiminomethanoimino)indeno[1,2-b]chromen-10-yl)carbamate, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeCascade reaction, Cyclization, Cycloaddition
Cascade reaction, substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-ones, substituted (E)-4-benzylidene-1-phenylpyrrolidine-2,3-diones, substituted (2R,3’R,4’S)-1”,3′-diphenyl-5′-thioxodispiro[indene-2,2′-pyrrolidine-4′,3”-pyrrolidine]-1,4”,5”(3H)-triones, (9R)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(4-nitrophenyl)amino]-4-[(4-nitrophenyl)amino]-3-Cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization
Henry reaction, 2-substituted ethyl 2-oxoacetate, nitromethane, 2-substituted ethyl (S)-2-hydroxy-3-nitro-propanoate, (9S)-cinchonan-6′,9-diol-9-benzoate, Cupreidine DerivativeHenry, Henry
Michael Addition, 1-oxoindan-2-carbonitrile, 2-chloroacrylonitrile, (S)-2-((R)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, Cupreidine BaseMichael, Michael Addition
Kinetic resolution, ethyl (E)-4-cyclopropyl-4-(1,3-dioxoisoindolin-2-yl)but-2-enoate, ethyl (R,E)-4-cyclopropyl-4-(1,3-dioxoisoindolin-2-yl)but-2-enoate, (8α,9R)-9-[[4,6-Bis(4-methoxyphenyl)-1,3,5-triazin-2-yl]oxy]-10,11-dihydro-6′-methoxy-Cinchonan, Dihydroquinine DerivativeKinetic resolution, Resolution
Vinylogous Aldol, 5H-2-furanone, aldehydes, hydroxyalkylfuranones, N-[(2S)-2-[[2-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3-phenylpropyl]-1,1,2,2,3,3,4,4,4-nonafluoro-1-Butanesulfonamide, Dihydroquinine DerivativeAldol, Vinylogous Aldol
Michael Addition, (E)-1,2,3-trifluoro-5-(2-nitrovinyl)benzene, diethyl malonate, diethyl (R)-2-(2-nitro-1-(3,4,5-trifluorophenyl)ethyl)malonate, Cupreidine BaseMichael, Michael Addition