Michael Addition, β,γ-unsaturated α-keto esters, α-nitro ketones, substituted methyl (Z)-2-acetoxy-5-nitropent-2-enoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Michael Addition, 6-chloro-3-nitro-2H-chromene, dimethyl malonate, dimethyl 2-((3S,4R)-6-chloro-3-nitrochroman-4-yl)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Spirocyclization, substituted ethyl (Z)-2-(1-benzyl-2-oxoindolin-3-ylidene)-2-cyanoacetate, phenols, spiro-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea,Quinine DerivativeSpirocyclization Spirocyclization, substituted 2H-chromen-2-one, substituted 2-methylene-1H-indene-1,3(2H)-dione, spirocyclic compound, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization Cyclization, cyclohexanone, substituted (E)-2-(2-nitrovinyl)phenol, substituted (4aS,9R,9aS)-9-(nitromethyl)-2,3,4,4a,9,9a-hexahydro-1H-xanthene, D-Proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition Addition, 3-fluoro-oxindoles, 1,1-bis(benzenesulfonyl)ethylene, 3-fluoro-3-substituted oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition Spirocyclization, oxindoles, N-protected (E)-3-benzylidenepyrrolidine-2,5-dione, N-protected ethyl (3aS,4R,5S,6R,6aS)-1,2′,3-trioxo-6-phenyl-4-(trifluoromethyl)-2,3,3a,4,6,6a-hexahydro-1H-spiro[cyclopenta[c]pyrrole-5,3′-indoline]-4-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization Aldol reaction, isatins, 2,2‐difluoro‐1,3‐diketones, substituted (S)-3-(1,1-difluoro-2-oxo-2-substituted-ethyl)-3-hydroxyindolin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Aldol Cyclization, enoates, unsaturated ketones, methyl (2R,3R,4S)-4-(4-methoxyphenyl)-2-(2-oxo-2-phenylethyl)-3-phenyl-3,4-dihydro-2H-pyran-6-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Cycloaddition, Diels-Alder reaction, Further Cyclizations Desymmetrization, substituted 2,4-dihydro-3H-pyrazol-3-one, cyclopentenediones, substituted 4-(5-hydroxy-1H-pyrazol-4-yl)cyclopent-4-ene-1,3-dione, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization« Older EntriesNext Entries »
Michael Addition, β,γ-unsaturated α-keto esters, α-nitro ketones, substituted methyl (Z)-2-acetoxy-5-nitropent-2-enoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Michael Addition, 6-chloro-3-nitro-2H-chromene, dimethyl malonate, dimethyl 2-((3S,4R)-6-chloro-3-nitrochroman-4-yl)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Spirocyclization, substituted ethyl (Z)-2-(1-benzyl-2-oxoindolin-3-ylidene)-2-cyanoacetate, phenols, spiro-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea,Quinine DerivativeSpirocyclization
Spirocyclization, substituted 2H-chromen-2-one, substituted 2-methylene-1H-indene-1,3(2H)-dione, spirocyclic compound, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization
Cyclization, cyclohexanone, substituted (E)-2-(2-nitrovinyl)phenol, substituted (4aS,9R,9aS)-9-(nitromethyl)-2,3,4,4a,9,9a-hexahydro-1H-xanthene, D-Proline, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition
Addition, 3-fluoro-oxindoles, 1,1-bis(benzenesulfonyl)ethylene, 3-fluoro-3-substituted oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAddition
Spirocyclization, oxindoles, N-protected (E)-3-benzylidenepyrrolidine-2,5-dione, N-protected ethyl (3aS,4R,5S,6R,6aS)-1,2′,3-trioxo-6-phenyl-4-(trifluoromethyl)-2,3,3a,4,6,6a-hexahydro-1H-spiro[cyclopenta[c]pyrrole-5,3′-indoline]-4-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization
Aldol reaction, isatins, 2,2‐difluoro‐1,3‐diketones, substituted (S)-3-(1,1-difluoro-2-oxo-2-substituted-ethyl)-3-hydroxyindolin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Aldol
Cyclization, enoates, unsaturated ketones, methyl (2R,3R,4S)-4-(4-methoxyphenyl)-2-(2-oxo-2-phenylethyl)-3-phenyl-3,4-dihydro-2H-pyran-6-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Cycloaddition, Diels-Alder reaction, Further Cyclizations
Desymmetrization, substituted 2,4-dihydro-3H-pyrazol-3-one, cyclopentenediones, substituted 4-(5-hydroxy-1H-pyrazol-4-yl)cyclopent-4-ene-1,3-dione, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeDesymmetrization
