Cyclization, vinylogous carbonyl enolates, substituted 2-nitroprop-2-en-1-ol, carbocycles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAlkylation, alpha-Alkylation, Cyclization, Cyclization, Further Cyclizations Cyclization, β,γ-unsaturated ketones, nitroalkenes, carbocycles, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeAddition, Cyclization, Cyclization, Further Cyclizations Mukaiyama-Michael Reaction, substituted (E)-(buta-1,3-dien-1-yloxy)trimethylsilane, substituted diisopropyl acryloylphosphonate, substituted benzyl (E)-4-formylhex-4-enoate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Mukaiyama-Michael Cascade reaction, 3-nitro-2 H-chromenes, acyclic enones, substituted 10a-nitro-1,4,4a,9,10,10a-hexahydrophenanthren-3(2H)-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations Atropisomer Synthesis, substituted 1,4-diethynylnaphthalene-2,3-diol, N/S-substituted sulfonyl(phenyl)methanamine, 1,4-distyrene-2,3-naphthalenediols, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis Atropisomer Synthesis, 1,3-dimethyl-5-tosylbenzo[k]phenanthridin-6(5H)-one, phenylmethanol, biaryl amino acids, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis Atropisomer Synthesis, N-arylindole lactams, alcohols, atropisomers, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution Michael Addition, 1,3-dicarbonyls, N-benzylmaleimide, 1-benzyl-3-(1,3-dicarbon-2-yl)pyrrolidine-2,5-diones, (8α,9R)-10,11-dihydro-11-mercapto-6′-methoxy-cinchonan-9-ol, Quinine DerivativeMichael, Michael Addition Atropisomer Synthesis, 2-fluoro-3-(2-fluorophenyl)-4-methylquinoline, benzenethiol, 3-arylquinolines, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-(1-methylethyl)-urea, Quinine DerivativeAtropisomer synthesis Cyclization, (E)-2′-(2-nitrovinyl)-[1,1′-biphenyl]-2-carbaldehydes, ketones, dibenzocycloheptanes, 3-[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCyclization« Older EntriesNext Entries »
Cyclization, vinylogous carbonyl enolates, substituted 2-nitroprop-2-en-1-ol, carbocycles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAlkylation, alpha-Alkylation, Cyclization, Cyclization, Further Cyclizations
Cyclization, β,γ-unsaturated ketones, nitroalkenes, carbocycles, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeAddition, Cyclization, Cyclization, Further Cyclizations
Mukaiyama-Michael Reaction, substituted (E)-(buta-1,3-dien-1-yloxy)trimethylsilane, substituted diisopropyl acryloylphosphonate, substituted benzyl (E)-4-formylhex-4-enoate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMichael Addition, Mukaiyama-Michael
Cascade reaction, 3-nitro-2 H-chromenes, acyclic enones, substituted 10a-nitro-1,4,4a,9,10,10a-hexahydrophenanthren-3(2H)-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeCascade reaction, Cyclization, Cyclization, Further Cyclizations
Atropisomer Synthesis, substituted 1,4-diethynylnaphthalene-2,3-diol, N/S-substituted sulfonyl(phenyl)methanamine, 1,4-distyrene-2,3-naphthalenediols, 3,4-Bis[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis
Atropisomer Synthesis, 1,3-dimethyl-5-tosylbenzo[k]phenanthridin-6(5H)-one, phenylmethanol, biaryl amino acids, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis
Atropisomer Synthesis, N-arylindole lactams, alcohols, atropisomers, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis, Dynamic Kinetic Resolution, Resolution
Michael Addition, 1,3-dicarbonyls, N-benzylmaleimide, 1-benzyl-3-(1,3-dicarbon-2-yl)pyrrolidine-2,5-diones, (8α,9R)-10,11-dihydro-11-mercapto-6′-methoxy-cinchonan-9-ol, Quinine DerivativeMichael, Michael Addition
Atropisomer Synthesis, 2-fluoro-3-(2-fluorophenyl)-4-methylquinoline, benzenethiol, 3-arylquinolines, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-(1-methylethyl)-urea, Quinine DerivativeAtropisomer synthesis
Cyclization, (E)-2′-(2-nitrovinyl)-[1,1′-biphenyl]-2-carbaldehydes, ketones, dibenzocycloheptanes, 3-[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCyclization
