Bifunctional Cinchona Alkaloid Catalyzed Vinylogous Michael Reaction of 3–Alkylideneoxindole with 4‐Oxo‐enoates: A Route to Chiral γ‐Keto Alkylideneoxindole Esters.

DOI Number:

10.1002/ajoc.202000227

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

3–alkylideneoxindole, 4‐oxo‐enoates

Product:

tert-butyl (S,E)-3-(5-(3-bromophenyl)-3-(ethoxycarbonyl)-5-oxo-1-phenylpentylidene)-2-oxoindoline-1-carboxylate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8