An asymmetric organocatalytic vinylogous Mannich reaction of 3-methyl-5-arylfuran-2(3H)-ones with N-(2-pyridinesulfonyl)imines: enantioselective synthesis of δ-amino γ,γ-disubstituted butenolides.
DOI Number:
10.1039/C7OB03117C
Reaction Category:
RXNO ID:
RXNO_0000032
Educt:
N-(2-pyridinesulfonyl)imines, 3-methyl-5-arylfuran-2(3H)-ones
Product:
δ-amino γ,γ-disubstituted butenolides
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7