Synthesis of chiral γ, γ-disubstituted γ-butenolides via direct vinylogous aldol reaction of substituted furanone derivatives with aldehydes.
DOI Number:
10.1021/acs.orglett.9b00574
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
aldehydes, 3,4,5-trisubstituted furan-2(3H)-one
Product:
substituted 5-(hydroxymethyl)furan-2(5H)-one
Catalyst:
N-[(2S)-2-[[2-[[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3-phenylpropyl]-1,1,2,2,3,3,4,4,4-nonafluoro-1-Butanesulfonamide
Cas No:
2093325-19-8
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7