Cinchona Alkaloid Squaramide-Catalyzed Asymmetric Ugi-Type Reaction of Isocyanoacetates with C,N-Cyclic Azomethine Imines: Access to Chiral Oxazole-Substituted Tetrahydroisoquinolines.

DOI Number:

10.1021/acs.joc.9b01955

Reaction Category:

Educt:

α-aryl-substituted isocyanoacetates, C,N-cyclic azomethine imines

Product:

C1-oxazole-substituted tetrahydroisoquinolines

Catalyst:

3-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1565829-19-7

Cas No:

522-66-7