Organocatalytic highly enantioselective tandem Michael–Knoevenagel reaction for the synthesis of substituted thiochromanes.

DOI Number:

10.1016/j.tetlet.2008.01.113
Link to literature

Reaction Category:

Cascade reaction

Educt:

2-mercaptobenzaldehyde, diethyl 2-(2-methoxybenzylidene)malonate

Product:

substituted thiochromanes

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7