Asymmetric Dearomative (3+2)-Cycloaddition Involving Nitro-Substituted Benzoheteroarenes under H-Bonding Catalysis.

DOI Number:

10.3390/molecules26164992
Link to literature

Reaction Category:

[3+2]-Cycloaddition | Cycloaddition

MOP ID:

MOP_0000715

Educt:

Substituted (Z)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one-2-nitrobenzofuran, nitro-substituted benzoheteroarenes

Product:

Substituted (1R,3S,3aS,8bS)-3a-nitro-1-(trifluoromethyl)-1,2,3a,8b-tetrahydrospiro[benzofuro[2,3-c]pyrrole-3,3'-indolin]-2'-one

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-86-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2