A highly enantioselective catalytic Strecker reaction of cyclic (Z)-aldimines.

DOI Number:

10.1039/C2CC31001E
Link to literature

Reaction Category:

Strecker

RXNO ID:

RXNO_0000207

Educt:

cyclic (Z)-aldimines, ethyl carbonocyanidate

Product:

(S)-spiro[cyclohexane-1,3'-indoline]-2'-carbonitrile

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7