Organocatalytic tandem enantioselective Michael-cyclization of isatin-derived β,γ-unsaturated α-ketoesters with 3-hydroxy-4 h-chromen-4-one or 2-hydroxy-1, 4-naphthoquinone derivatives.
DOI Number:
10.1039/C6RA17400K
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
isatin-derived β,γ-unsaturated α-ketoesters, substituted 3-hydroxy-4H-chromen-4-one
Product:
spirocycles
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7