Organocatalytic tandem enantioselective Michael-cyclization of isatin-derived β,γ-unsaturated α-ketoesters with 3-hydroxy-4 h-chromen-4-one or 2-hydroxy-1,4-naphthoquinone derivatives.
DOI Number:
10.1039/C6RA17400K
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
isatin-derived β,γ-unsaturated α-ketoesters, substituted 2-hydroxy-1,4-naphthoquinone
Product:
spirocycles
Catalyst:
N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-(4-nitrophenyl)-thiourea
Cas No:
1360198-77-1
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0