Enantioselective construction of CF3-Containing Spirooxindole γ-Lactones via organocatalytic asymmetric michael/lactonization.

DOI Number:

10.1021/acs.orglett.8b04039
Link to literature

Reaction Category:

Cascade reaction | Spirocyclization

Educt:

3-hydroxyoxindoles, 3-fluoroethylidene oxindoles

Product:

spirooxindoles

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1407166-63-5

Associated Product from Buchler GmbH:

Dihydroquinidine Base

Cas No:

1435-55-8