Bifunctional Squaramide‐Catalyzed Asymmetric [3+2] Annluation Reactions of 2‐Isothiocyanato‐1‐indanones with 2‐Arylidene‐1, 3‐indanediones.

DOI Number:

10.1002/slct.202203142
Link to literature

Reaction Category:

[3+2] Annulation | Cyclization | Further Cyclizations | Spirocyclization

MOP ID:

MOP_0000561

Educt:

2‐Isothiocyanato‐1‐indanones, 2‐Arylidene‐1,3‐indanediones

Product:

substituted (S)-5'-thioxodispiro[indene-2,2'-pyrrolidine-4',2''-indene]-1,1'',3''(3H)-trione

Catalyst:

3-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione

Cas No:

1256245-85-8

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0