Enantioselective synthesis of highly substituted chromans via the oxa-Michael–Michael cascade reaction with a bifunctional organocatalyst.

DOI Number:

10.1021/acs.joc.5b01751

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

substituted (2E)-3-(2-hydroxyphenyl)prop-2-enon, nitroalkenes

Product:

substituted chromans

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Cas No:

130-95-0