Enantioselective synthesis of trifluoromethyl‐substituted 2‐isoxazolines: asymmetric hydroxylamine/enone cascade reaction.
DOI Number:
10.1002/ange.201002065
Reaction Category:
MOP ID:
MOP_0000561
Educt:
(E)-4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, hydroxylamine
Product:
(S)-3,5-diphenyl-5-(trifluoromethyl)-4,5-dihydroisoxazole
Catalyst:
(8α,9R)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide
Cas No:
217299-06-4
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0