Enantioselective synthesis of trifluoromethyl‐substituted 2‐isoxazolines: asymmetric hydroxylamine/enone cascade reaction.

DOI Number:

10.1002/ange.201002065

Reaction Category:

Educt:

(E)-4,4,4-trifluoro-1,3-diphenylbut-2-en-1-one, hydroxylamine

Product:

(S)-3,5-diphenyl-5-(trifluoromethyl)-4,5-dihydroisoxazole

Catalyst:

(8α,9R)-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide

Cas No:

217299-06-4

Cas No:

130-95-0