Asymmetric Domino Multicatalysis for the Synthesis of 3-Substituted Phthalides: Cinchonine/NHC Cooperative System.

DOI Number:

10.1021/ol5000617
Link to literature

Reaction Category:

Cyclization | Further Cyclizations | Intramolecular cyclization | Lactonization | Michael Addition | Oxa-Michael Addition

MOP ID:

MOP_0000561

Educt:

substituted 2-vinylbenzoic acid

Product:

substituted (R)-3-methylisobenzofuran-1(3H)-one

Catalyst:

Cinchonine Base

Cas No:

118-10-5

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5