Catalytic enantioselective synthesis of atropisomeric biaryls by a cation-directed O-alkylation.

DOI Number:

10.1038/nchem.2710

Reaction Category:

MOP ID:

MOP_0000369

Educt:

C/O-substituted 2'-hydroxy-3,4-dihydro-[1,1'-binaphthalen]-2(1H)-one, benzyl iodide

Product:

atropisomeric biaryls

Catalyst:

(9S)-9-hydroxy-6′-methoxy-1-[(2,3,4-trifluorophenyl)methyl]-cinchonanium bromide

Cas No:

949028-87-9

Cas No:

56-54-2