Enyne diketones as substrate in asymmetric Nazarov cyclization for construction of chiral allene cyclopentenones.

DOI Number:

10.1038/s41467-022-30846-y

Reaction Category:

RXNO ID:

RXNO_0000209

Educt:

methyl 2-diazo-2-phenylacetate, (E)-4-methyl-1-phenylhex-4-en-1-yn-3-ol

Product:

(S)-5-hydroxy-2,3-dimethyl-5-phenyl-4-((R)-2-phenylvinylidene)cyclopent-2-en-1-one

Catalyst:

N,N′-bis[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea

Cas No:

1263049-13-3

Cas No:

130-95-0