Asymmetric synthesis of dihydrocoumarins containing contiguous quaternary and tertiary stereogenic centers catalyzed by a cinchona‐alkaloid‐based bifunctional thiourea derivative.

DOI Number:

10.1002/adsc.201500666

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

substituted (E)-3-(2-hydroxyphenyl)-1-substituted-prop-2-en-1-one, substituted oxazol-5(4H)-one

Product:

dihydrocoumarins

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7