Efficient organocatalytic asymmetric synthesis of 2-amino-4H-chromene-3-carbonitrile derivatives.

DOI Number:

10.1016/j.tetasy.2012.02.019
Link to literature

Reaction Category:

Cyclization | Cyclization | Further Cyclizations | Michael | Michael Addition

MOP ID:

MOP_0000561

Educt:

substituted (E)-2-(2-nitrovinyl)phenol, malononitrile

Product:

2-amino-4H-chromene-3-carbonitriles

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7