Control of diastereoselectivity in tandem asymmetric reactions generating nonadjacent stereocenters with bifunctional catalysis by cinchona alkaloids.
DOI Number:
10.1021/ja0670409
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
S-methyl 2-cyanopropanethioate, 2-chloroacrylonitrile
Product:
S-methyl (2R,4R)-4-chloro-2,4-dicyano-2-methylbutanethioate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-25-8
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2