Asymmetric Michael addition of α-fluoro-α-nitroalkanes to nitroolefins: facile preparation of fluorinated amines and tetrahydropyrimidines.
DOI Number:
10.1039/C4CC03513E
Reaction Category:
Educt:
(E)-1,3-difluoro-5-(2-nitrovinyl)benzene, (fluoro(nitro)methyl)benzene
Product:
1,3-difluoro-5-((1R,2S)-1-fluoro-1,3-dinitro-1-phenylpropan-2-yl)benzene
Catalyst:
(2S,3R)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-butanamide
Cas No:
1381859-85-3
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2