Organocatalytic regioselective asymmetric Michael addition of azlactones to o-hydroxy chalcone derivatives.

DOI Number:

10.1039/C5OB00121H

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

azlactones, o-hydroxy chalcones

Product:

(R)-2-((S)-1-(5-chloro-2-hydroxyphenyl)-3-(4-iodophenyl)-3-oxopropyl)-2,4-diphenyloxazol-5(2H)-one

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7