Highly Enantioselective Michael Addition of 2‐Oxindole‐3‐carboxylate Esters to Nitroolefins Promoted by Cinchona Alkaloid‐Thiourea‐Brønsted Acid Cocatalysts.

DOI Number:

10.1002/adsc.201200206

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

2‐oxindole‐3‐carboxylate esters, nitroolefins

Product:

substituted (S)-3-(2-nitroethyl)-2-oxoindoline-3-carboxylate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7