Organocatalytic Asymmetric Conjugate Addition of 2‐Oxindole‐3‐Carboxylate Esters to 2‐Phthalimido Acrylates: Efficient Synthesis of Cγ‐tetrasubstituted α‐Amino Acid Derivatives.

DOI Number:

10.1002/ajoc.201300292

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

2‐oxindole‐3‐carboxylate esters, 2‐phthalimido acrylates

Product:

ethyl (S)-3-((S)-2-(1,3-dioxoisoindolin-2-yl)-3-ethoxy-3-oxopropyl)-1-methyl-2-oxoindoline-3-carboxylate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7