Enantioselective Synthesis of Quaternary α-Aminophosphonates via Conjugate Addition of α-Nitrophosphonates to Enones.

DOI Number:

10.1021/ol203132h
Link to literature

Reaction Category:

Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

1-(3,4-dimethoxyphenyl)prop-2-en-1-one, diethyl (1-nitropentyl)phosphonate

Product:

diethyl (1-(3,4-dimethoxyphenyl)-4-nitro-1-oxooctan-4-yl)phosphonate

Catalyst:

N-[(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-yl]-N′-(4-nitrophenyl)thiourea

Cas No:

1360198-80-6

Associated Product from Buchler GmbH:

Dihydroquinine Base

Cas No:

522-66-7