Catalytic asymmetric synthesis of α,β-disubstituted α,γ-diaminophosphonic acid precursors by michael addition of α-substituted nitrophosphonates to nitroolefins.
DOI Number:
10.1021/ol3012666
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
α-substituted nitrophosphonates, nitroolefins
Product:
diethyl ((2S,3R)-2-nitro-3-(nitromethyl)octan-2-yl)phosphonate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7